Overview
- Presents comprehensive coverage of the function of activation and detoxification enzymes
- Clear enough to appeal to trainees; authoritative enough to appeal to advanced resarchers
- Presents new chapters on Oxidative and Electrophilic Stresses, Metabolic Conversions and Liver Toxicity
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Table of contents (19 chapters)
Keywords
About this book
This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry. The book will also be valuable to advanced researchers. The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers. This new edition is updated throughout andfeatures completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway.
Authors and Affiliations
About the author
Chang-Hwei Chen, PhD, is a biophysicist at the Institute of Health and the Environment, Professor Emeritus of Department of Biomedical Sciences at the School of Public Health, and Former Adjunct Professor of Physics at the University of Albany, Albany, New York
Bibliographic Information
Book Title: Activation and Detoxification Enzymes
Book Subtitle: Functions and Implications
Authors: Chang-Hwei Chen
DOI: https://doi.org/10.1007/978-3-031-55287-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024
Hardcover ISBN: 978-3-031-55286-1Published: 14 April 2024
Softcover ISBN: 978-3-031-55289-2Due: 15 May 2024
eBook ISBN: 978-3-031-55287-8Published: 13 April 2024
Edition Number: 2
Number of Pages: XXI, 251
Number of Illustrations: 50 b/w illustrations
Topics: Human Physiology, Enzymology, Pharmacology/Toxicology, Nutrition, Bioinformatics
Industry Sectors: Biotechnology, Consumer Packaged Goods, Health & Hospitals, Pharma