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Activation and Detoxification Enzymes

Functions and Implications

  • Book
  • © 2024
  • Latest edition

Overview

  • Presents comprehensive coverage of the function of activation and detoxification enzymes
  • Clear enough to appeal to trainees; authoritative enough to appeal to advanced resarchers
  • Presents new chapters on Oxidative and Electrophilic Stresses, Metabolic Conversions and Liver Toxicity
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Table of contents (19 chapters)

Keywords

About this book

This book discusses the many advances in the understanding of the functions and implications of activation and detoxification enzymes. This organized, concise overview will meet the needs of those who are initially exposed to this important subject, particularly for students and researchers in the areas of biomedical sciences, biochemistry, nutrition, pharmacology, and chemistry.  The book will also be valuable to advanced researchers.  The book discusses subjects associated with foreign-compound-metabolizing enzymes with emphasis on biochemical aspects, including lipophilic foreign compounds, activation and detoxification enzymes, metabolic enzyme catalytic properties, reactive metabolic intermediates, biomedical and biochemical effects, genetic polymorphisms, enzyme inducibility, enzyme modulation for health benefits, dietary-related enzyme modulators, and structural characteristics of enzyme inducers.  This new edition is updated throughout andfeatures completely new chapters on Oxidative and Electrophilic Stresses, Metabolite- Mediated Disease Conditions, and Defense Mechanism: Nrf2-ARE Pathway. 

Authors and Affiliations

  • Institute for Health, and the Environment and Department of Biomedical Sciences, University at Albany, State University of New York, Albany, USA

    Chang-Hwei Chen

About the author

Chang-Hwei Chen, PhD, is a biophysicist at the Institute of Health and the Environment, Professor Emeritus of Department of Biomedical Sciences at the School of Public Health, and Former Adjunct Professor of Physics at the University of Albany, Albany, New York 


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