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Introduction

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Continuum Modeling in Mechanobiology

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Abstract

This chapter provides some historical background on mechanobiology and discusses the differences between biomechanics and mechanobiology. The processes of growth, remodeling, and morphogenesis are introduced, and an overview of some of the challenges encountered in mathematical modeling of biological systems are given. Finally, the chapter reviews some of the biology used in this book, with an emphasis on developmental biology.

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Notes

  1. 1.

    In fact, my own definition of mechanobiology has evolved over the years (Taber 2016).

  2. 2.

    Interestingly, tissue engineering has been around since at least the mid-1900s (Hayashi and Boehm 1952)

  3. 3.

    Residual stress is the stress remaining in a body when all external loads are removed.

  4. 4.

    Just my opinion, based on decades of experience with modeling.

  5. 5.

    Additional biology specific to growth and remodeling will be included in chapters that focus on these subjects.

  6. 6.

    Motor proteins move along filaments using energy provided by ATP hydrolysis.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Washington University, St. Louis, MO, USA

    Larry A. Taber

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  1. Larry A. Taber
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Taber, L.A. (2020). Introduction. In: Continuum Modeling in Mechanobiology. Springer, Cham. https://doi.org/10.1007/978-3-030-43209-6_1

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  • DOI: https://doi.org/10.1007/978-3-030-43209-6_1

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  • Print ISBN: 978-3-030-43207-2

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