Abstract
Along the recent medical history there is an ubiquitous myth surrounding smegma; its nature, composition, its beneficial role or deleterious effects either in health or in diseases. Those scientist who want to advocate circumcision are usually dissimulate behind smegma; incriminating it to induce cancer not only in the harbouring man but also in his partner, this normal substance has been causally linked to cervical, prostatic and penile cancers. Any preputial pathology for which a clear aetiology has not been established, the smegma is usually incriminated. On the other hand; those who want to struggle against preputial cut are pretending a sophisticated function of smegma in fighting against infection and they magnifying its role in normal sexual life. Some of circumcision zealots had irrefutable dogma about the smegma, but if smegum is dangerous by its nature we will prove that circumcision will not eliminate it, but only circumcision will just make it invisible.
Even the historical perspective of medical ideas pertaining to smegma is confusing, but over the past two centuries there are many researches investigated the smegma in details and impartially.
The other problem in the previous studies that most of the observations have been extrapolated to the human from other mammals, and this may leads to misinterpretation of the nature and function of smegma.
We will discuss the origin, nature, and role of smegma, and two new points will be elaborated; firstly the genital sites other than the preputial sac have also producing smegma, and secondly smegma itself had no shedding cells or cell desquamations, it is just a genital sebum.
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References
Van Howe RS, Hodges FM. The carcinogenicity of smegma: debunking a myth. J Eur Acad Dermatol Venereol. 2006;20:1046–54.
Hyman AB, Brownstein MH. Tyson’s “glands.” Ectopic sebaceous glands and papillomatosis penis. Arch Dermatol. 1969;99:31–6.
Velazquez EF, Cold CJ, Barreto JE, Cubilla AL. Penis and distal urethra. In: Mills SE, editor. Histology for pathologists, vol. 965. Philadelphia: Lippincott Williams & Wilkins; 2007.
Wright J. How smegma serves the penis: Nature’s assurance that the uncircumcised glans penis will function smoothly is provided by smegma. Sexology. 1970;37(2):50–3.
O’Neill HJ, Gershbein LL. Lipids of human and equine smegma. Oncology. 1976;33(4):161–6. https://doi.org/10.1159/000225134.
Parkash S, Jeyakumar S. Human subpreputial collection: its nature and formation. J Urol. 1973;110(2):211–2. https://doi.org/10.1016/s0022-5347(17)60164-2.
Fleiss PM, Hodges FM, Van Howe RS. Immunological functions of the human prepuce. Sex Transm Infect. 1998;74(5):364–7. https://doi.org/10.1136/sti.74.5.364.
Anyanwu LJ, Kashibu E. Microbiology of smegma in boys in Kano, Nigeria. J Surg Res. 2012;173(1):21–5. https://doi.org/10.1016/j.jss.2011.04.057.
Frohlich E, Schaumburg-Lever G, Klessen C. Immunelectron microscopic localization of cathepsin B in human exocrine glands. J Cutan Pathol. 1993;20:54–60.
Chung JM, et al. Microbiology of smegma: prospective comparative control study. Investig Clin Urol. 2019;60:127–32. https://doi.org/10.4111/icu.2019.60.2.127.
Anyanwu LJ, Kashibu E, Edwin CP, Mohammad AM. Microbiology of smegma in boys in Kano, Nigeria. J Surg Res. 2012;173:21–5.
O’Hara K, O’Hara J. The effect of male circumcision on the sexual enjoyment of the female partner. BJU Int. 1999;83:79–84.
Fröhlich E, Schaumburg-Lever G, Klessen C. Immunelectron microscopic localization of cathepsin B in human exocrine glands. J Cutan Pathol. 1993;20:54–60.
Majocchi D. Ueber die smegmogenen Concretionen des Präputialsackes “Smegmolithen” und über die Analogie zwischen diesen und anderen Epidermisconcretionen des Menschen und einiger Säugethiere. Arch F Dermat. 1902;59:9–26. https://doi.org/10.1007/BF01822886.
D’arcy McCrea E. Chapter XIII - Injuries of the penis. Phimosis and paraphimosis. Preputial calculi. In: Diseases of the urethra and penis. Amsterdam: Butterworth-Heinemann; 2013. p. 232–45. https://doi.org/10.1016/B978-1-4831-6791-6.50016-8.
Batistatou A, Panelos J, Zioga A, Charalabopoulos KA. Ectopic modified sebaceous glands in human penis. Int J Surg Pathol. 2006;14(4):355–6. https://doi.org/10.1177/1066896906291779.
Øster J. Further fate of the foreskin. Incidence of preputial adhesions, phimosis, and smegma among Danish schoolboys. Arch Dis Child. 1968;43(228):200–3. https://doi.org/10.1136/adc.43.228.200.
Fahmy M. Chapter 36: Smegmoma “smegma collection in health and disease”. In: Congenital anomalies of the penis. Cham: Springer; 2017. https://doi.org/10.1007/978-3-319-43310-3.
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Fahmy, M.A.B. (2020). Smegma. In: Normal and Abnormal Prepuce. Springer, Cham. https://doi.org/10.1007/978-3-030-37621-5_17
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DOI: https://doi.org/10.1007/978-3-030-37621-5_17
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