Historical Aspects of Fungal Infections

  • Nikolaos Ch. Syrmos
  • Vaitsa Giannouli
  • Mehmet Turgut


Searching the historical perspective of fungal origins, Hippocrates appears to be the first physician to describe the cases of candidiasis in his book Epidemics. Afterward, however, fungal infections concerning the central nervous system (CNS) seem to receive little attention in scientific community. CNS infections usually have a variety of presentations and manifestations, depending on the particular characteristics and immune status of patient. In this chapter, a brief historical presentation of findings regarding fungal infections of the CNS from “Ancient Greece” to “Mid Modern Period” and “Contemporary Period” is presented, documented, and discussed briefly.


Fungal infections History of medicine Ancient Greece Mid Modern Period Contemporary Period Central nervous system 



Central nervous system


Cerebrospinal fluid


United States of America


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Nikolaos Ch. Syrmos
    • 1
  • Vaitsa Giannouli
    • 1
  • Mehmet Turgut
    • 2
  1. 1.Medical SchoolAristotle University of ThessalonikiThessalonikiGreece
  2. 2.Department of NeurosurgeryAydın Adnan Menderes University School of MedicineAydınTurkey

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