Fungal Infections of the Central Nervous System

Pathogens, Diagnosis, and Management

  • Mehmet Turgut
  • Sundaram Challa
  • Ali Akhaddar

Table of contents

  1. Front Matter
    Pages i-xii
  2. General Considerations

    1. Front Matter
      Pages 1-1
    2. Nikolaos Ch. Syrmos, Vaitsa Giannouli, Mehmet Turgut
      Pages 3-9
    3. Chandrasekhar Srinivasamurthy Banushree, Neriyana Sannappa Madhusudhan
      Pages 31-42
    4. Shruti Gupta, Sanjay Behari
      Pages 43-49
    5. Leonardo F. Jurado, Rocío del Pilar López-Panqueva
      Pages 51-73
    6. Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti
      Pages 75-88
  3. Fungal Pathogens: Pathogenesis, Pathology and Diagnosis

    1. Front Matter
      Pages 89-89
    2. Sundaram Challa
      Pages 91-105
    3. M. Altay Atalay
      Pages 107-120
    4. A. Serda Kantarcioglu
      Pages 121-154
    5. María del Rocío Reyes-Montes, Maria Lucia Taylor, Esperanza Duarte-Escalante, María Guadalupe Frías-De-León
      Pages 155-166
    6. Anita Mahadevan, Shankar Krishna Susarla
      Pages 167-185
    7. María Guadalupe Frías-De-León, Erick Martínez-Herrera, María del Rocío Reyes-Montes, Gustavo Acosta-Altamirano
      Pages 187-194
    8. Hurriyet Deniz Ozgun, Darren L. Jacobs, Steven A. Toms
      Pages 195-204
  4. Clinical Syndromes of Fungal Infections Involving Central Nervous System and Its Coverings

    1. Front Matter
      Pages 235-235
    2. Ali Akhaddar
      Pages 237-243
    3. Alexa Bodman, Walter A. Hall
      Pages 245-251
    4. Hasan Emre Aydın, Ismail Kaya
      Pages 253-257
    5. Manish Jaiswal
      Pages 259-267
    6. Erdal Kalkan, Fatih Erdi, Yasar Karatas, Bülent Kaya
      Pages 269-274
    7. Manogaran Ravi Sankar, Mathialagan Arulalan, Amit K. Keshri, Arun K. Srivastava, Awadhesh K. Jaiswal, Sanjay Behari
      Pages 275-288
    8. Jagarlapudi M. K. Murthy, Subhendu Parida
      Pages 289-293
    9. Gauri S. Mankekar, Rahul Mehta, Daniel W. Nuss
      Pages 295-303
    10. Forhad Hossian Chowdhury, Mohammod Raziul Haque, Mohammod Zahed Hossain, Mainul Haque Sarker
      Pages 305-325
    11. Ali Akhaddar, Sylma Diabira
      Pages 327-334
    12. Arsovska Anita, Arsovski Zoran
      Pages 335-343
    13. Álynson Larocca Kulcheski, Xavier Soler I. Graells, André Luís Sebben
      Pages 345-350
  5. Radiologıcal Findings of Fungal Infections Involving Central Nervous System and Its Coverings

    1. Front Matter
      Pages 351-351
    2. Subhendu Parida
      Pages 353-365
    3. Ahmet T. Turgut, Elif Başbay Gündoğdu, Can Başaloğlu, Mehmet Turgut
      Pages 367-386
    4. Jitender Saini, Mudit Gupta, Rakesh K. Gupta
      Pages 393-404
  6. Therapy of Fungal Infections Involving Central Nervous System and Its Coverings

    1. Front Matter
      Pages 405-405
    2. Mehmet Turgut
      Pages 407-414
  7. Further Insights into Fungal Infections

    1. Front Matter
      Pages 421-421
    2. Turan C. Dülgeroğlu, Mehmet Turgut
      Pages 423-430
    3. Yaşar Barış Turgut, Gökhan Sargın, Özgür Tanrıverdi
      Pages 431-439
    4. Yaşar Barış Turgut, Gökhan Sargın, Gökhan Pektaş
      Pages 441-449
    5. Güliz Uyar Güleç, Yaşar Barış Turgut
      Pages 463-469
    6. Dwarakanath Srinivas, Harsh Deora
      Pages 471-474
    7. Neeraj Kumar, Ravindra Kumar Garg, Hardeep Singh Malhotra
      Pages 475-478
  8. Back Matter
    Pages 479-479

About this book


This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.


Invasive aspergillosis Candidiasis Antifungal agents Disseminated mucormycosis Immunosuppression Disseminated cryptococcosis Histoplasmosis Cryptococcal meningitis Neurosurgical procedures

Editors and affiliations

  • Mehmet Turgut
    • 1
  • Sundaram Challa
    • 2
  • Ali Akhaddar
    • 3
  1. 1.Department of NeurosurgeryAydın Adnan Menderes University, School of MedicineAydınTurkey
  2. 2.Department of PathologyBasavatarakam Indo-American Hospital & Research InstituteHyderabadIndia
  3. 3.Department of Neurosurgery, Avicenne Military HospitalMohammed V University in RabatMarrakechMorocco

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-06087-9
  • Online ISBN 978-3-030-06088-6
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals