This chapter will briefl y review the major aspects of the molecular virology and replication of HBV, and summarize the major viral mutants of clinical signifi cance that are associated with drug resistance. Also, the factors and mechanisms of drug resistance in hepatitis B will be discussed. Finally, strategies to prevent the emergence of drug resistance will be addressed.
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Locarnini, S. (2009). The Hepatitis B Virus and Antiviral Drug Resistance: Causes, Patterns, and Mechanisms. In: Mayers, D.L. (eds) Antimicrobial Drug Resistance. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-59745-180-2_37
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DOI: https://doi.org/10.1007/978-1-59745-180-2_37
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