Antimicrobial Drug Resistance

Mechanisms of Drug Resistance

  • Douglas L. Mayers

Part of the Infectious Disease book series (ID)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. General Overview

    1. George A. Jacoby
      Pages 3-7
    2. Fernando Baquero, Rafael Cantón
      Pages 9-32
    3. G. L. Drusano
      Pages 33-42
  3. General Mechanisms of Drug Resistance

    1. Maja Babic, Robert A. Bonomo
      Pages 65-74
    2. Louis B. Rice
      Pages 75-80
    3. Vanessa D'Costa, Gerard D. Wright
      Pages 81-95
    4. Joseph B. McPhee, Sandeep Tamber, Michelle D. Brazas, Shawn Lewenza, Robert E. W. Hancock
      Pages 97-110
    5. Adrian R. Walmsley, Barry P. Rosen
      Pages 111-120
    6. Christoph A. Fux, Paul Stoodley, Mark Shirtliff, J. William Costerton
      Pages 121-131
  4. Bacterial Drug Resistance – Mechanisms

    1. André Zapun, Pauline Macheboeuf, Thierry Vernet
      Pages 145-170
    2. Maria L. Magalhães, John S. Blanchard
      Pages 171-181
    3. Marilyn C. Roberts, Stefan Schwarz
      Pages 183-193
    4. Varsha V. Moudgal, Glenn W. Kaatz
      Pages 195-205
    5. George A. Jacoby
      Pages 207-210
    6. Annie Canu, Roland Leclercq
      Pages 211-221
    7. Abhay Dhand, David R. Snydman
      Pages 223-227

About this book


The volumes included in Antimicrobial Drug Resistance represent the first comprehensive, multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives.

The first volume, Antimicrobial Drug Resistance, Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant strains, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of currently available ones.

The second volume, Antimicrobial Drug Resistance, Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious disease physician requires input from the clinical microbiologist and infection control specialist to make informed choices for the effective treatment of various strains of drug-resistant pathogens in individual patients.

This 2-volume set is an important reference for students in microbiology, infectious disease physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.


Drug HIV Handbook Hepatitis Malaria Mayers Resistance Schistosomiasis Virus antibiotics antimicrobial antimicrobial resistance antiviral drug bacteria epidemiological

Editors and affiliations

  • Douglas L. Mayers
    • 1
  1. 1.Executive Vice President & Chief Medical Offi cerIdenix PharmaceuticalsCambridgeUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-60327-592-7
  • Online ISBN 978-1-59745-180-2
  • About this book
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