Abstract
Since the first description of the syndrome of acute respiratory distress in adults (ARDS) in 1967 [1], there has been considerable debate concerning its exact definition. Specifically, distinguishing the syndrome from acute lung injury (ALI) has only recently been addressed. The relevance of the pulmonary hypertension that complicates ARDS and its role in the pathophysiology of the accompanying acute respiratory failure has also been the subject of investigation. ARDS has been defined recently as noncardiogenic pulmonary edema with refractory hypoxemia (Pao2 / FIO2 ratio < 27 kPa), associated with bilateral infiltrates on chest radiography [2].
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Grover, E.R., Bihari, D. (1996). Inhaled Nitric Oxide Therapy. In: Evans, T.W., Haslett, C. (eds) ARDS Acute Respiratory Distress in Adults. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3430-7_29
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DOI: https://doi.org/10.1007/978-1-4899-3430-7_29
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