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Abstract

The development of silicon polymer membranes [1–4] for prolonged extracorporeal circulation stimulated the idea of using extracorporeal support systems in the treatment of the syndrome of acute respiratory distress in adults (ARDS). This disease is characterized primarily by severe impairment in pulmonary gas exchange, reduced compliance and radiological manifestation of interstitial and/or intra-alveolar edema. The clinical course of ARDS following the acute inflammatory phase is often complicated and prolonged by factors associated with therapeutic interventions such as mechanical ventilation. As ARDS progresses, high inspired oxygen concentrations as well as high mean airway pressures may be required to ensure adequate arterial oxygenation.

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Pappert, D., Rossaint, R., Gerlach, H., Falke, K.J. (1996). Extracorporeal Membrane Oxygenation. In: Evans, T.W., Haslett, C. (eds) ARDS Acute Respiratory Distress in Adults. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3430-7_25

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