Apoptosis and Its Regulation

  • J. John Cohen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 406)


There is only one popular way to be conceived, but a myriad of ways to die. We die from some external force, such as an accident or foul play, or else from “natural causes”. It is interesting how good the parallel is with the cells out of which we are made. All our somatic cells arise by the process of mitosis, regardless of their location in the body or their ultimate destiny. And these cells die by either of two processes, roughly equivalent to accidents and natural causes. Just as a pathologist will determine cause of death by examining the body, we distinguish the two forms of cell death by morphology1.


Programme Cell Death Suicide Gene Final Common Pathway Immature Thymocyte Cell Death Gene 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • J. John Cohen
    • 1
  1. 1.Department of ImmunologyUniversity of Colorado Medical SchoolDenverUSA

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