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Apoptosis and Its Regulation

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Mechanisms of Lymphocyte Activation and Immune Regulation VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 406))

Abstract

There is only one popular way to be conceived, but a myriad of ways to die. We die from some external force, such as an accident or foul play, or else from “natural causes”. It is interesting how good the parallel is with the cells out of which we are made. All our somatic cells arise by the process of mitosis, regardless of their location in the body or their ultimate destiny. And these cells die by either of two processes, roughly equivalent to accidents and natural causes. Just as a pathologist will determine cause of death by examining the body, we distinguish the two forms of cell death by morphology1.

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  1. Department of Immunology, University of Colorado Medical School, Denver, Colorado, 80262, USA

    J. John Cohen

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  1. University of California, Irvine, Irvine, California, USA

    Sudhir Gupta

  2. University of Colorado Health Sciences Center, Denver, Colorado, USA

    J. John Cohen

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Cohen, J.J. (1996). Apoptosis and Its Regulation. In: Gupta, S., Cohen, J.J. (eds) Mechanisms of Lymphocyte Activation and Immune Regulation VI. Advances in Experimental Medicine and Biology, vol 406. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0274-0_2

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  • DOI: https://doi.org/10.1007/978-1-4899-0274-0_2

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