Reflex Control of Respiratory Activity (Short Overview)

  • Giuseppe Sant’Ambrogio


All the several respiratory related activities can be modified by environmental stimuli, changes in energy requirements as well as by various behavioral functions like vocalization, emotional expressions, olfaction etc... These changes involve striated muscles acting on the respiratory bellows and the upper airway, tracheobron-chial smooth muscles and mucus glands, blood vessels supplying various districts of the respiratory apparatus, etc...


Vagal Afferents Cold Receptor High Rest Heart Rate Pulmonary Stretch Receptor Cervical Vagotomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    F.W. Zechman, Jr., J. Salzano and F.G. Hall, Effect of cooling the cervical vagi on the work of breathing, J.Appl.Physiol. 12:301 (1958).PubMedGoogle Scholar
  2. 2.
    T.P.K. Lim, U.C. Luft and F. S. Grodins, Effects of cervical vagotomy on pulmonary ventilation and mechanics, J.Appl. Physiol. 13: 317 (1958).PubMedGoogle Scholar
  3. 3.
    A. Guz, M.I.M. Noble, J.G. Widdicombe, D. Trenchard and W.W. Mushin, The effect of bilateral block of vagus and glossopharyngeal nerves on the ventilatory response to CO2 of conscious man. Respir.Physiol. 1:206 (1966).PubMedCrossRefGoogle Scholar
  4. 4.
    S. T. Kuna, G. E. Woodson, and G. Sant’Ambrogio, Effect of laryngeal anesthesia on pulmonary function testing in normal subjects, Am.Rev.Respir.Dis. 137: 656 (1988).PubMedCrossRefGoogle Scholar
  5. 5.
    D. Bartlett, Jr., Effects of vagal afferents on laryngeal responses to hypercapnia and hypoxia, Respir.Physiol. 42: 189 (1980).PubMedCrossRefGoogle Scholar
  6. 6.
    D. Bartlett, Jr., S. L. Knuth and K. V. Knuth, Effects of pulmonary stretch receptor blockade on laryngeal responses to hypercapnia and hypoxia, Respir.Physiol. 45: 67 (1981).PubMedCrossRefGoogle Scholar
  7. 7.
    N. R. Banner, A. Guz, R. Heaton, J.A. Innes, K. Murphy and M. Yacoub, Ventilatory and circulatory responses at the onset of exercise in man following heart or heart-lung transplantation, J.Physiol.Lond. 399:437 (1988).PubMedGoogle Scholar
  8. 8.
    T. Higenbottam, B. A. Otulana, and J. Wallwork,. The Physiology of heart-lung transplantation in humans, NIPS 5: 71 (1990).Google Scholar
  9. 9.
    H. Pontoppidan and H. K. Beecher, Progressive loss of protective reflexes in the airway with the advance of age, J.A.M.A. 174: 77 (1960).CrossRefGoogle Scholar
  10. 10.
    B. Bishop, Reflex control of abdominal muscles during positive pressure breathing, J.Appl. Physiol. 19: 224 (1964).PubMedGoogle Scholar
  11. 11.
    A. Davies, F.B. Sant’Ambrogio and G. Sant’Ambrogio, Control of postural changes of end expiratory volume (FRC) by airways slowly adapting mechanoreceptors, Respir.Physiol. 41: 211 (1980).PubMedCrossRefGoogle Scholar
  12. 12.
    H. Sellick and J. G. Widdicombe, The activity of lung irritant receptors during pneumothorax, hyperpnea and pulmonary vascular congestion, J.Physiol.Lond. 203: 359 (1969).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Giuseppe Sant’Ambrogio
    • 1
  1. 1.Department of Physiology and BiophysicsThe University of Texas Medical Branch at GalvestonGalvestonUSA

Personalised recommendations