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Requirements for Production Targets for Middle-Energy Cyclotrons

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Chemists’ Views of Imaging Centers
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Abstract

The fundamental requirements of production target systems are much the same for all accelerators: They must provide with boring regularity, predictably sufficient amounts of radionuclide of consistently satisfactory quality and quantity. The details of the methods by which these goals are achieved varies with the beam energy and current capabilities of the cyclotron, the types of particles accelerated, and other factors.

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References

  1. A.P. Wolf, and W.B. Jones; Cyclotrons for Biomedical Radioisotope Production, Radiochem. Acta, 34:, 1–7, 1983

    CAS  Google Scholar 

  2. R. Finn, B. Dahl; Facility Layout and Planning, Chap 5. in Proceedings. of the second Workshop on Targetry and Target Chemistry, Heidelberg, West Germany, September 22–25, 1987

    Google Scholar 

  3. P.W. Wojciechowski, M. Sajjad, R.M. Lambrecht; A Semi-Quantitative Approach to the Design, Analysis and Operation of a Gas Target System; Appl. Radiat. Isot., Part A, Int. J. Appl. Instrum., 39, (5), 429–436, 1988

    Article  CAS  Google Scholar 

  4. B.W. Weiland; A Negative Ion Cyclotron Using 11 MeV Protons for Production of Radionuclides for Clinical Positron Tomography, 119–125, Proceeding of the First International Workshop on Targetry and Target Chemistry, Heidelberg West Germany, 4 to 7 Oct. 1985

    Google Scholar 

  5. Y. Jongen; Cyclone 30, a H’, K-30, 500uA Cyclotron, 164–165, Proceedings, of the second Workshop on Targetry and Target Chemistry, Heidelberg, West Germany, September 22–25, 1987

    Google Scholar 

  6. M.R. Kilbourn, J.T. Hood, M.J. Welch; A Simple 180 Water Target for 18F Production, Int. J. Appl. Rad. Isot., 35, (7), 599–602, 1984

    Article  CAS  Google Scholar 

  7. R. Iwata, T. Ido, F. Brady, T. Takahashi, A. Ujiie; [18F]Fluoride Production with a Circulating [18O] Water Target; Appl. Radiat. Isot., Part A, Int. J. Radiat. A.pl. Instrum., 38, (11), 979–984, 1987

    Article  CAS  Google Scholar 

  8. R.J. Nickles, R.D. Hichwa, M.E. Daube, G.D. Hutchins, D.D. Congdon; An 18O2-Target for the High Yield Production of 18F-Fluoride, int. J. Appl. Radiat. Isot.; 34, (3), 625–629, 1983

    Article  CAS  Google Scholar 

  9. J. Gorres, K.U. Kettner, H. Krawinkel, C. Rolfs; The Influence of Intense Ion Beams on Gas Target Densities; Nucl. Inst, and Meth., 177, 295–303, 1980

    Article  Google Scholar 

  10. S.-J. Heselius, P. Lindblom, O. Solin; Optical Studies of the Influence of an Intense Ion Beam on High Pressure Gas Target; Int. J. Appl. Radiat. Isot., 33, 653–659, 1982

    Article  CAS  Google Scholar 

  11. S.-J. Heselius, P. Malmborg, O. Solin, B. Langstrom; Studies of Proton Beam Penetration in Nitrogen-gas Targets with Respect to Production and Specific Radioactivity of Carbon-11; Appl. Radiat. Isot. Part A, 38, (1), 49–57, 1987

    Article  CAS  Google Scholar 

  12. M. Oselka, J.E. Gindler; Non-linear Behavior of Gas Targets for Isotope Production; Int. J. Appl. Rad. & Isot., 28, 804–805, 1977

    Article  CAS  Google Scholar 

  13. N. Jarmie, L.J. Morrison, J. C. Martin; Thin Metal Windows for Gas Targets, Nuclear Inst. & Meth., 116, 451–452, 1974

    Article  CAS  Google Scholar 

  14. H.H. Stevens, Behavior of Circular Membranes Stretched above the Elastic Limit by Air Pressure; Soc. for Experimental Stress Anal. Proc, 2, (1), 139–146, 1944

    Google Scholar 

  15. G.T. Bida, R.L. Ehrenkaufer, A.P. Wolf, J.S. Fowler, R.R. MacGregor, T.J. Ruth; The Effect of Target-gas Purity on the Chemical Form of F-18 during 18F-F2 Production Using the Neon/Fluorine Target; J. Nucl. Med., 21, (8), 758–762, 1980

    PubMed  CAS  Google Scholar 

  16. V. Casella, T. Ido, A.P. Wolf, J.S. Fowler, R.R. MacGregor, T.J. Ruth; Anhydrous F-18 Labeled Elemental Fluorine for Radiopharmaceutical Preparation; J. Nucl. Med., 21, (8), 750–757, 1980

    PubMed  CAS  Google Scholar 

  17. M. Diksic, Y. Toda; Production of F18-labeled Molecular Fluorine with a Medical mini-Cyclotron; Can. J. Chem., 61, (4), 661–664, 1983

    Article  CAS  Google Scholar 

  18. J. Keinonen, A. Fontell, A.-L. Kairento; Effective Small-Volume [18O]Water Target for the Production of [18F]fluoride; Appl. Radiat. Isot., Part A, Int. J. Radiat. Appl. Instrum., 37, (7), 631–632, 1986

    Article  CAS  Google Scholar 

  19. B.W. Wieland, D.J. Schlyer, A.P. Wolf; Charged Particle Penetration in Gas Targets Designed for Accelerator Production of Radionuclides Used in Nuclear Medicine; Int. J. Appl. Radiat. Isot., 35, 5, 387–396, 1984

    Article  CAS  Google Scholar 

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Dahl, J.R. (1995). Requirements for Production Targets for Middle-Energy Cyclotrons. In: Emran, A.M. (eds) Chemists’ Views of Imaging Centers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9670-4_38

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  • DOI: https://doi.org/10.1007/978-1-4757-9670-4_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9672-8

  • Online ISBN: 978-1-4757-9670-4

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