Abstract
Macrophages are the mature elements of the mononuclear phagocyte system (MPS) (Langevoort et al., 1970; Van Furth et al., 1972). This system was developed as a result of severe criticism of the original concept of the reticuloendothelial system (Aschoff, 1924) and comprises all cells that show avid phagocytosis. The mononuclear phagocyte concept considers all macrophages to be the recent progeny of bone marrow-derived monocytes, which traverse the circulation en route to various sites of the body, where they are needed in host defense processes.
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References
Akagawa, K. S., Kamoshita, A., and Tokunaya, T., 1988, Effects of granulocyte-macrophage colony-stimulating factor-1 on the proliferation and differentiation of murine alveolar macrophages, J. Im-monol. 141: 3383–3390.
Aschoff, L., 1924, Das reticulo-endotheliale system, Ergehn. Inn. Med. Kinderheilk. 26: 1–5.
Austyn, J. M., and Gordon, S., 1981, F4/80, a monoclonal antibody directed specifically against the mouse macrophage, Eur. J. Immunol. 11: 805–815.
Baccarini, M., Kiderlen, A. F., Decker, T., and Lohmann-Matthes, M. L., 1986, Functional heterogeneity of murine macrophage precursor cells from spleen and bone marrow, Cell. Immunol. 101: 339–350.
Baccarini, M., Hao, L., and Decker, T., 1988, Macrophage precursors as natural killer cells against tumor cells and microorganisms, Nat. Immun. Cell. Growth Regul. 7: 316–327.
Bainton, D. F. 1980, Changes in peroxidase distribution within organelles of blood monocytes and peritoneal macrophages after surface adherence in vitro and in vivo, in Mononuclear Phagocytes: Functional Aspects ( R. Van Furth, ed.), pp. 61–86, Martinus Nijhoff, The Hague.
Beelen, R. H. J., and Fluitsma, D. M., 1982, What is the relevance of exudate-resident macrophages? Immunobiology 161: 266–273.
Beelen, R. H. J., and Walker, W. S., 1983, Dynamics of cytochemically distinct subpopulations of macrophages in elicited rat peritoneal exudates, Cell. Immunol. 82: 246–257.
Beelen, R. H. J., Broekhuis-Fluitsma, D. M., Kornfeld, C., and Hoefsmit, E. C. M., 1978, Identification of exudate-resident macrophage on the basis of peroxidatic activity, J. Reticuloendothel. Soc. 23: 103–110.
Beelen, R. H. J., Fluitsma D. M., Van der Meer, J. W. M., and Hoefsmit, E. C. M., 1979, Development of different peroxidatic activity patterns in peritoneal macrophages in vivo and in vitro, J. Reticuloendothel. Soc. 25: 513–523.
Beelen, R. H. J., Fluitsma, D. M., and Hoefsmit, E. C. M., 1980, The cellular composition of omentum milky spots and the ultrastructure of milky spot macrophages and reticulum cells, J. Reticuloendothel. Soc. 28: 585–599.
Berman, J. W., and Busch, R. S., 1985, Thy-1 antigen expression by murine hematopoietic precursor cells, Exp. Hematol. 13: 1152–1156.
Bitterman, P. B., Saltzmann, L. E., Adelberg, S., Ferrans, V. J., and Crystal, R. G., 1984, Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in chronically inflamed lung, J. Clin. Invest. 74: 460–469.
Blok, J., Onderwater, J. J. M., de Water, R., and Ginsel, L. A., 1982, A cytochemical method for the demonstration of 5’-nucleotidase in mouse peritoneal macrophages, with cerium ions used as trapping agent, Histochemistry 75: 437–443.
Blussé van Oud Alblas, A., and Van Furth, R., 1979, Origin, kinetics and characteristics of pulmonary macrophages in the normal steady state, J. Exp. Med. 149: 1504–1511.
Blussé van Oud Alblas, A., and Van Furth, R., 1982, The origin of pulmonary macrophages, Immunobiology 161: 186–192.
Blussé van Oud Alblas, A., Van der Linden-Schrever, B., and Van Furth, R., 1981, Origin and kinetics of pulmonary macrophages during an inflammatory reaction induced by intravenous administration of heat-killed bacillus Calmette-Guerin, J. Exp. Med. 154: 235–252.
Blussé van Oud Alblas, A., Mattie, H., and Van Furth, R., 1983, A quantative evaluation of pulmonary macrophage kinetics, Cell Tissue Kinet. 16: 276–281.
Bodel, P. T., Nichols, B. A., and Bainton, D. F., 1977, Appearance of peroxidase reactivity within the rough endoplasmic reticulum of blood monocytes after surface adherence, J. Exp. Med. 145: 264–274.
Bodel, P. T., Nichols, B. A., and Bainton, D. F., 1978, Differences in peroxidase localization of rabbit peritoneal macrophages after surface adherence, Am. J. Pathol. 91: 107–118.
Boswell, H. S., Wade, P. M., and Quesenberry, P. J., 1984, Thy-I antigen expression by murine high-proliferative capacity hematopoietic progenitor cells, J. Immunol. 133: 2940–2949.
Bouwens, L., and Wisse, E., 1985, Proliferation, kinetics, and fate of monocytes in rat liver during a zymosan-induced inflammation, J. Leukocyte Biol. 37: 531–543.
Bouwens, L., Baekeland, M., and Wisse, E., 1984, Importance of local proliferation in the expanding Kupffer cell population of rat liver after zymosan stimulation and partial hepatectomy, Hepatology 4: 213–219.
Bouwens, L., Baekeland, M., De Zanger, R., and Wisse, E., 1986a, Quantitation, tissue distribution and proliferation kinetics of Kupffer cells in normal rat liver, Hepatology 6: 718–722.
Bouwens, L., Knook, D. L., and Wisse, E., 1986b, Local proliferation and extrahepatic recruitment of liver macrophages (Kupffer cells) in partial-body irradiated rats, J. Leukocyte Biol. 39: 687–697.
Bowden, D. H., and Adamson, I. Y. R., 1980, Role of monocytes and interstitial cells in the generation of alveolar macrophages. J. Kinetic studies of normal mice, Lab. Invest. 42: 511–517.
Breatnach, A. S., 1978, Development and differentiation of dermal cells of man, J. Invest. Dermatol. 71: 2–8.
Bursuker, I., and Goldman, R., 1982, Distinct bone marrow precursors for mononuclear phagocytes expressing high and low 5’-nucleotidase activity, J. Cell. Physiol. 112: 237–242.
Bursuker, I., and Goldman, R., 1983, On the origin of macrophage heterogeneity: A hypothesis, J. Reticuloendothel. Soc. 33: 207–220.
Bursuker, I., Thodes, J. M., and Goldman, R., 1982, 0-Galactosidase—an indicator of the maturational stage of mouse and human mononuclear phagocytes, J. Cell. Physiol. 112: 385–390.
Byrne, P. V., Guilbert, L. J., and Stanley, E. R., 1981, Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues, J. Cell. Biol. 31: 848–853.
Coggle, J. E., and Tarling, J. D., 1984, The proliferation kinetics of pulmonary alveolar macrophages, J. Leukocyte Biol. 35: 317–327.
Cohn, Z. A., and Benson, B., 1965, The differentiation of mononuclear phagocytes. Morphology, cytochemistry and biochemistry, J. Exp. Med. 121: 153–170.
Crofton, R. W., Diesselhoff-den Dulk, M. M. C., and Van Furth, R., 1978, The origin, kinetics, and characteristics of the Kupffer cells in the normal steady state, J. Exp. Med. 148: 1–17.
Cross, M., Mangelsdorf, I., Wedel, A., and Renkawitz, R., 1988, Mouse lysozyme M gene: Characterization and expression studies, Proc. Natl. Acad. Sci. USA 85: 6232–6236.
Daems, W. Th., 1980, Peritoneal macrophages, in The Reticuloendothelial System, a Comprehensive Treatise, Vol. 1, Morphology ( I. Carr and W. Th. Daems, eds.), pp. 57–127, Plenum Press, New York.
Daems, W. Th., and De Bakker, J. M., 1982, Do resident macrophages proliferate? Immunobiology 161: 204–211.
Dantschakoff, W., 1908, Untersuchungen uber die Entwicklung des Blutes and des Bindegewebes bei den Vogeln. I. Die erste Entstehung der blutbildenes Organ, Anat. Hefte, Wiesb. 37: 471–479.
Dawd, D. S., and Hinchcliff, J. R., 1971, Cell death is the “opaque path” in the central mesenchyme of the developing chick limb: A cytological, cytochemical, and electron microscope analysis, J. Embryo!. Exp. Morphol. 26: 401–424.
De Bakker, J. M., 1983, On the origin of peritoneal resident macrophages, Thesis, University of Leiden, Leiden, The Netherlands.
De Bakker, J. M., and Daems, W. Th., 1981, The heterogeneity of mouse peritoneal macrophages, in Heterogeneity of Mononuclear Phagocytes ( O. Landy, and M. Landy, eds.), pp. 11–13, Academic Press, London.
De Bakker, J. M., De Wit, L., and Daems, W. Th., 1981, The relation between monocytes and resident (tissue) macrophages, in Haematology and Blood Transfusion, Vol. 27, Disorders of the Monocyte-Macrophage System ( F. Schmalzl, D. Huhn, and H. E. Schaefer, eds.), pp. 79–89, Springer-Verlag, Berlin.
De Bakker, J. M., De Wit, A. W., Onderwater, J. J. M., Ginsel, L. A., and Daems, W. Th., 1985a, On the origin of peritoneal resident macrophages. I: DNA synthesis in mouse peritoneal resident macrophages, J. Submicrosc. Cytol. 17: 133–139.
De Bakker, J. M., De Wit, A. W., Woelders, H., Ginsel, L. A., and Daems, W. Th., 1985b, On the origin of peritoneal resident macrophages. II: Recovery of the resident macrophage population in the peritoneal cavity and in the milky spots after peritoneal cell depletion, J. Submicrosc. Cytol. 17: 141–151.
De Bakker, J. M., De Wit, A. W., Koerten, H. K., Ginsel, L. A., and Daems, W. Th., 1985c, On the origin of peritoneal resident macrophages. III: EM-immunocytochemical studies on the origin of mouse peritoneal resident macrophages, J. Submicrosc. Cytol. 17: 153–159.
Decker, T., Baccarini, M., and Lohmann-Matthes, M. L., 1986a, Liver-associated macrophage precursors as natural cytotoxic effectors against Candida albicans and Yac-1 cells, Eur. J. Immunol. 16: 693–699.
Decker, T., Baccarini, M., and Lohmann-Matthes, M. L., 1986b, Bone marrow-independent induction of organ-associated macrophage precursors, Immunobiology 173: 383–389.
DeFelici, M., Heasman, J., Wylie, C. C., and McLaren, A., 1986, Macrophages in the urogenital ridge of the mid-gestation mouse fetus, Cell Differ. 18: 119–129.
Deimann, W., and Fahimi, H. D., 1978, Peroxidase cytochemistry and ultrastructure of resident macrophages in fetal rat liver. A developmental study, Dev. Biot. 66: 43–56.
Deimann, W., Seitz, M., Gemsa, D., and Fahimi, H. D., 1984, Endogenous peroxidase in the nuclear envelope and endoplasmic reticulum of human monocytes in vitro: Association with arachidonic acid metabolism, Blood 64: 491–498.
De Water, R., Van’t Noordende, J. M., Ginsel, L. A., and Daems, W. Th., 1981, Heterogeneity in wheatgerm agglutinin binding by mouse peritoneal macrophages, Histochemistry 72: 333–339.
De Water, R., Van Blitterswijk, C. A., Daems, W. Th., and Ginsel, L. A., 1982, Heterogeneity ofconcanavalin A binding by mouse peritoneal macrophages, Histochemistry 74: 301–307.
De Water, R., Ginsel, L. A., de Bakker, J. M., Blok, J., and Daems, W. Th., 1984a, Cytochemical probes for the characterization of peritoneal macrophages, in Mononuclear Phagocyte Biology ( A. Volkman, eds.), pp. 167–188, Marcel Dekker, New York.
De Water, R., Van’t Noordende, J. M., Daems, W. Th., and Ginsel, L. A., 1984b, Wheat-germ agglutinin binding in four types of mouse peritoneal macrophage: A quantitative EM-cytochemical study, Histochemistry 80: 449–456.
De Water, R., Van der Meer, J. W. M., Van’t Noordende, J. M., Onderwater, J. J. M., Van de Gevel, J. S., and Ginsel, L. A., 1985, Expression of 5’-nucleotidase activity and wheat germ agglutinin binding sites in mononuclear phagocytes from bone-marrow cultures, J. Leukocyte Biol. 37: 263–277.
Diesselhoff-den Dulk, M. M. C., Crofton, R. W., and Van Furth, R., 1979, Origin and kinetics of Kupffer cells during an acute inflammatory response, Immunology 37: 7–14.
Dougherty, G. J., and McBride, W. H., 1984, Macrophage heterogeneity, J. Clin. Lab. Immunol. 14: 1–11.
Evans, M. J., Shami, S. G., and Martinez, L. A., 1986, Enhanced proliferation of pulmonary alveolar macrophages after carbon installation in mice depleted of blood monocytes by strontium-89, Lab. Invest. 54: 154–159.
Ginsel, L. A., 1987, F4/80 and peroxidatic activity of macrophages, J. Histochem. Cytochem. 35: 1168–1170.
Ginsel, L. A., De Water, R., Onderwater, J. J. M., Blok, J., and Daems, W. Th., 1983, Heterogeneity in 5’-nucleotidase activity of mouse peritoneal macrophages. An EM-cytochemical and biochemical study, Histochemistry 79: 295–309.
Ginsel, L. A., de Water, R., Blok, J., and Daems, W. Th., 1984, Cell-surface heterogeneity in mouse peritoneal macrophages: 5’-Nucleotidase and wheat-germ agglutinin binding, in Tissue Culture and RES ( P. Rölich and E. Bâcsy, eds.), pp. 11–25, Akadémia Kiadb, Budapest.
Ginsel, L. A., Rijfkogel, L. P., and Daems, W. Th., 1985a, A dual origin of macrophages? Review and hypothesis, in Macrophage Biology ( S. Reichert and M. Kojima, eds.), pp. 621–649, Alan R. Liss, New York.
Ginsel, L. A., De Water, R., Van der Meer, J. W. M., and Daems, W. Th., 1985b, Heterogeneity of 5’-nucleotidase activity and wheat-germ agglutinin binding in mononuclear phagocytes, in Mononuclear Phagocytes: Characteristics, Physiology and Function ( R. Van Furth, ed.), pp. 99–113, Martinus Nijhoff, Dordrecht.
Ginsel, L. A., De Goede, R., Huisman, E., Rook, M., Van’t Noordende, J. M., and Onderwater, J. J. M., 1992, Origin of resident macrophages and their (PO-negative) precursor cultured from mouse blood samples, submitted.
Golde, D. W., and Lisken, A. B., 1974, Proliferative capacity of human alveolar macrophage, Nature (London) 247: 373–375.
Gordon, S., 1986, Biology of the macrophage, J. Cell Sci. Suppl. 4: 267–286.
Gordon, S., Crocker, P., Lee, S. H., Morris, L., and Raboniwitz, S., 1986, Trophic and defense functions of murine macrophages, in Mechanisms of Host Resistance to Infectious Agents, Tumors, and Allografts ( R. M. Steinman and R. J. North, eds.), pp. 121–137, Rockefeller University Press, New York.
Goud, T. J. L. M., and Van Furth, R., 1975, Proliferative characteristics of monoblasts grown in vitro, J. Exp. Med. 142: 1200–1217.
Goud, T. J. L. M., Schotte, C., and Van Furth, R., 1975, Identification and characterization of the mono-blast in mononuclear phagocyte colonies grown in vitro, J. Exp. Med. 142: 1180–1199.
Hirsch, S., Austyn, J. M., and Gordon, S., 1981, Expression of the macrophage specific antigen F4/80 during differentiation of mouse bone marrow cells in culture, J. Exp. Med. 154: 713–725.
Hume, D. A., Robinson, A. P., MacPherson, G. G., and Gordon, S., 1983, The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs, J. Exp. Med. 158: 1522–1536.
Janossy, G., Bofill, M., Poultner, L. W., Rawlings, E., Burford, G. D., Navarret, C., Ziegler, A., and Kelemen, E., 1986, Separate ontogeny of two macrophage-like accessory cell populations in the human fetus, J. Immunol. 136: 4354–4361.
Langevoort, H. L., Cohn, Z. A., Hirsch, J. G., Humphrey, J. H., Spector, W. G., and Van Furth, R., 1970, The nomenclature of mononuclear phagocytic cells. Proposal for a new classification, in Mononuclear Phagocytes ( R. van Furth, ed.), pp. 1–6, Blackwell Scientific, Oxford.
Lee, K. C., 1980, On the origin and mode of action of functionally distinct macrophage subpopulations, Mol. Cell. Biochem. 30: 39–55.
Lee, S. H., Starkey, P. M., and Gordon, S., 1985, Quantitative analysis of total macrophage content in adult mouse tissues, Immunochemical studies with monoclonal antibody F4/80, J. Exp. Med. 161: 475–489.
Leenen, P. J. M., Jansen, A. M. A. C., and Ewijk, W. V., 1986, Murine macrophage cell lines can be ordered in a linear differentiation sequence, Differentiation 32: 157–164.
Leenen, P. J. M., Slieker, W. A. T., Melis, M., and Van Ewijk, W., 1990a, Murine macrophage precursor characterization I. Production, phenotype and differentiation of macrophage precursor hybrids, Eur. J. Immunol. 20: 15–25.
Leenen, P. J. M., Melis, M., Slieker, W. A. T., and Van Ewijk, W., 1990b, Murine macrophage precursor characterization 11. Monoclonal antibodies against macrophage precursor antigens, Eur. J. Immunol. 20: 27–34.
Lin, H. S., Kuhn, C., and Kuo, T., 1975, Clonal growth of hamster free alveolar cells in soft agar, J. Exp. Med. 142: 877–886.
Lin, H. S., Lokeshwar, B. L., and Hsu, S., 1989, Both granulocyte-macrophage CSF and macrophage CSF control the proliferation and survival of the same subset of alveolar macrophages, J. Immunol. 142: 515–519.
Lohmann-Matthes, M. L., Domzig, W., and Roder, J., 1979, Promonocytes have the functional characteristics of natural killer cells, J. Immunol. 123: 1883–1886.
Lombard, Y., Bartholeyns, J., Chockri, M., Illinger, D., Hartmann, D., Dumont, S., Kaufmann, S. H. E., Landmann, R., Loor, F., and Poindron, P., 1988, Establishment and characterization of long-term cultured cell lines of murine resident macrophages, J. Leukocyte Biol. 44: 391–401.
Malorny, U., Michels, E., and Sorg, C., 1986, A monoclonal antibody against an antigen present on mouse macrophages and absent from monocytes, Cell Tissue Res. 243: 421–428.
Maximow, A., 1909, Der Lymphozyt als gemeinsame Stammzelle der verschiedenen Blutelemente in der embryonalen Entwicklung and im postfoetalen Leben der Saugetiere, Folia Haematol. 8: 125–132.
Melnicoff, J. J., Horan, P. K., Breslin, E. W., and Morahan, P. S., 1988, Maintenance of peritoneal macrophages in the steady state, J. Leukocyte Biol. 44: 367–375.
Melnicoff, M. J., Horan, P. K., and Morahan, P. S., 1989, Kinetics of changes in peritoneal cell populations following acute inflammation, Cell. Immunol. 118: 178–191.
Metcalf, D., 1984, The Hemopoietic Colony Stimulating Factors, Elsevier, Amsterdam.
Metcalf, D., 1988, The Molecular Control of Blood Cells, Harvard University Press, Cambridge, Mass.
Moore, M. A. S., and Owen, J. J. T., 1965, Chromosome marker studies on the development of the haemopoietic system in the chick embryo, Nature (London) 208: 965–967.
Moore, M. A. S., and Owen, J. J. T., 1967, Stem cell migration in developing myeloid and lymphoid systems, Lancet 1: 658–659.
Morahan, P. S., Volkman, A., Melnicoff, M. J., and Dempsey, W. L., 1988, Macrophage heterogeneity, in Macrophages and Cancer ( G. H. Heppner and A. Fulton, eds.), p. 1–37, CRC Press, Boca Raton, Fla.
Naito, M., Takahashi, K., Takahashi, H., and Kojima, M., 1982, Ontogenetic development of Kupffer cells, in Sinusoidal Liver Cells ( E. Wisse and D. L. Knook, eds.), pp. 155–161, Elsevier Biomedical Press, Amsterdam.
Naito, M., Yamamura, F., Nishikawa, S. J., and Takahashi, K., 1989, Development, differentiation and maturation of fetal mouse yolk sac macrophages in cultures, J. Leukocyte Biol. 46: 1–10.
Naito, M., Takahashi, K., and Nishikawa, S., 1990, Development, differentiation, and maturation of macrophages in the fetal mouse liver, J. Leukocyte Biol. 48: 27–37.
Nakata, K., Akagawa, K. S., Fukayama, M., Hayashi, Y., Kadokura, M., and Tokunaya, T., 1991, Granulocyte-macrophage colony-stimulating factor promotes the proliferation of human alveolar macrophages in vitro, J. Immunol. 147: 1266–1272.
Neumann, C., and Sorg, C., 1980, Sequential expression of functions during macrophage differentiation in murine bone marrow liquid cultures, Eur. J. Immunol. 10: 834–840.
Nibbering, P. H., Leijh, P. C. J., and Van Furth, R., 1987, Quantitative immunocytochemical characterization of mononuclear phagocytes. I. Monoblasts, promonocytes, monocytes, and peritoneal and alveolar macrophages, Cell. Immunol. 105: 374–385.
Nicola, N. A., 1987, Why do hemopoietic growth factor receptors interact with each other? Immunol. Today 8: 134–140.
Noga, S. J., Normann, S. J., and Weiner, R. S., 1984, Methods in laboratory investigation, isolation of guinea pig monocytes and Kurloff cells: Characterization of monocyte subsets by morphology, cytochemistry, and adherence, Lab. Invest. 51: 244–252.
Ogawa, M., Porter, P. N., and Nakahata, T., 1983, Renewal and commitment to differentiation of hemopoietic stem cells (an interpretive review), Blood 61: 823–829.
Oka, K., Miyazaki, M., and Kojima, M., 1982, An electron microscopical study on peroxidase activity of rabbit monocytes, resident and exudate macrophages, Acta Pathol. Jpn. 32: 445–460.
Papadimitriou, J. M., and Ashman, R. B., 1989, Macrophages: Current views on their differentiation, structure, and function, Ultrastruct. Pathol. 13: 343–372.
Sawyer, R. T., 1986a, The ontogeny of pulmonary alveolar macrophages in parabiotic mice, J. Leukocyte Biol. 40: 347–353.
Sawyer, R. T. 1986b, The significance of local resident pulmonary alveolar macrophage proliferation to population renewal, J. Leukocyte Biol. 39: 77–87.
Sawyer, R. T., Strausbauch, P. H., and Volkman, A., 1982, Resident macrophage proliferation in mice depleted of blood monocytes by strontium-89, Lab. Invest. 46: 165–170.
Shellito, J., Esparza, C., and Armstrong, C., 1987, Maintenance of the normal rat alveolar macrophage cell population, Am. Rev. Respir. Dis. 135: 78–82.
Shibata, Y., and Volkman, A., 1985a, The effect of bone marrow depletion on prostaglandin E-producing suppressor macrophages in mouse spleen, J. Immunol. 135: 3897–3904.
Shibata, Y., and Volkman, A., 1985b, The effect of hemopoietic microenvironment on splenic suppressor macrophages in congenitally anemic mice of genotype SI/SI3, I Immunol. 135: 3905–3910.
Springer, T. A., 1980, Cell-surface differentiation in the mouse. Characterization of “jumping” and “lineage” antigens using xenogeneic rat monoclonal antibodies, in Monoclonal Antibodies. Hybridomas; A New Dimension in Biological Analysis ( R. H. Kennett, T. J. McKearn, and K. B. Bechtol, eds.), pp. 305–313, Academic Press, New York.
Stewart, C., Lin, H., and Adles, C., 1978, Proliferation and colony-forming activity of peritoneal exudate cells in liquid culture, J. Exp. Med. 147: 1253–1259.
Takahashi, K., Yamamura, F., and Naito, M., 1989, Differentiation, maturation and proliferation of macrophages in the mouse yolk sac: A light-microscopic, enzyme-cytochemical, immunohistochemical, and ultrastructural study, J. Leukocyte Biol. 45: 87–96.
Tarling, J. D., Lin, H. S., and Hsu, S., 1987, Self-renewal of pulmonary alveolar macrophages: Evidence from radiation chimera studies, J. Leukocyte Biol. 42: 443–446.
Thompson, J., and Van Furth, R., 1970, The effect of glucocorticosteroids on the kinetics of mononuclear phagocytes, J. Exp. Med. 131: 429–449.
Thompson, J., and Van Furth, R., 1973, The effect of glucocorticosteroids on the proliferation and kinetics of promonocytes in the bone marrow, J. Exp. Med. 137: 10–21.
Treves, A. J., 1984, The origin of monocyte-macrophage heterogeneity: Possible alternatives, Med. Hypothes. 14: 335–346.
Van der Meer, J. W. M., Beelen, R. H. J., Fluitsma, D. M., and Van Furth, R., 1979, Ultrastructure of mononuclear phagocytes developing in liquid bone marrow cultures: A study on peroxidative activity, J. Exp. Med. 149: 17–26.
Van der Meer, J. W. M., Van de Gevel, J. S., and Van Furth, R., 1983, Characteristics of long-term cultures of proliferating, mononuclear phagocytes from bone marrow, J. Reticuloendothel. Soc. 34: 203–225.
Van der Meer, J., Van de Gevel, J. S., De Water, R., Ginsel, L. A., Wouters, C., Daems, W. Th., and Van Furth, R., 1985, Proliferation and differentiation of mononuclear phagocytes in vitro, in Mononuclear Cells (R. Van Furth, ed.), pp. 243–254, Martinus Nijhoff, The Hague.
Van Furth, R., 1980, Cells of the mononuclear phagocyte system. Nomenclature in terms of sites and conditions, in Mononuclear Phagocytes: Functional Aspects ( R. Van Furth, ed.), pp. 1–30, Martinus Nijhoff, The Hague.
Van Furth, R., 1981, Current view of the mononuclear phagocyte system, in Haematology and Blood Transfusion, Vol. 27, Disorders of the Monocyte-Macrophage System ( F. Schmalzl, D. Huhn, and H. E. Schaefer, eds.), pp. 3–10, Springer-Verlag, Berlin.
Van Furth, R., 1988, Phagocytic cells: Development and distribution of mononuclear phagocytes in normal steady state and inflammation, in Inflammation: Basic Principles and Clinical Correlates (J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds.), pp. 281–295, Raven Press, New York.
Van Furth, R., 1989, Origin and turnover of monocytes and macrophages, in Cell Kinetics of the Inflammatory Reaction (O. H. Iversen, ed.), Current Topics in Pathology, pp. 125–150, Springer-Verlag, Heidelberg.
Van Furth, R., and Cohn, Z. A., 1968, The origin and kinetics of mononuclear phagocytes, J. Exp. Med. 128: 415–433.
Van Furth, R., and Diesselhoff-den Dulk, M. M. C., 1970, The kinetics of promonocytes and monocytes in the bone marrow, J. Exp. Med. 132: 813–828.
Van Furth, R., and Diesselhoff-den Dulk, M. M. C., 1982, Characterization of mononuclear phagocytes from the mouse, guinea pig, rat, and man, Inflammation 6: 39–53.
Van Furth, R., and Diesselhoff-den Dulk, M. M. C., 1984, Dual origin of mouse spleen macrophages, J. Exp. Med. 160: 1273–1283.
Van Furth, R., and Sluiter, W., 1986, Distribution of blood monocytes between a marginating and a circulating pool, J. Exp. Med. 163: 474–479.
Van Furth, R., Cohn, Z. A., Hirsch, J. G., Humphrey, J. H., Spector, W. G., and Langevoort, H. L., 1972, The mononuclear phagocyte system: A new classification of macrophages, monocytes and their precursor, Bull. WHO 46: 845–852.
Van Furth, R., Diesselhoff-den Dulk, M. M. C., and Mattie, H., 1973, Quantitative study on the production and kinetics of mononuclear phagocytes during an acute inflammatory reaction, J. Exp. Med. 138: 1314–1321.
Van Furth, R., Diesselhoff-den Dulk, M. M. C., Sluiter, W., and Van Dissel, J. T., 1985, New perspectives on the kinetics of mononuclear phagocytes, in Mononuclear Phagocytes: Characteristics, Physiology and Function ( R. Van Furth, ed.), pp. 201–208, Martinus Nijhoff, Dordrecht.
Van Rooijen, N., Kors, N., and Kraal, G., 1989, Macrophage subset repopulation in the spleen: Differential kinetics after liposome-mediated elimination, J. Leukocyte Biol. 45: 97–104.
Volkman, A., Chang, N. C., Strausbauch, P. H., and Morahan, P. S., 1983, Differential effects of chronic monocyte depletion on macrophage populations, Lab. Invest. 49: 291–298.
Walker, W. S., 1982. Macrophage functional heterogeneity, Adv. Exp. Med. Biol. 155: 435–441.
Walker, W. S., 1987, Origins of macrophage diversity: Functional and phenotypic analysis of cloned populations of mouse splenic macrophages, Cell. Immunol. 107: 417–432.
Walker, W. S., and Hester, R. B., 1983, The functional heterogeneity of macrophages, in The Reticuloen- dothelial System ( J. A. Bellanti and H. B. Herscowitz, eds.), pp. 27–42, Plenum Press, New York.
Walker, E. B., Akporiaye, E. T. Warner, N. L., and Stewart, C. C., 1985, Characterization of subsets of bone marrow-derived macrophages by flow cytometry analysis, J. Leukocyte Biol. 37: 121–136.
Warnock, M. L., Sniezek, M., and Shellito, J., 1987, Endogenous peroxidase activity as a marker of macrophage renewal during BCG-induced inflammation in the rat, Am. J. Pathol. 128: 171–180.
Watt, S. M., Karhi, K., Gatter, K., Furley, A. J. W., Katz, F. E., Healy, L. E., Altass, L. J., Bradley, N. J., Sutherland, D. R., Levinsky, R., and Greaves, M. F., 1987, Distribution and epitope analysis of the cell membrane glycoprotein (HPCA-1) associated with human hemopoietic progenitor cells, Leukemia 1: 417–426.
Werb, Z., and Chin, J. R., 1983, Onset of apoprotein E secretion during differentiation of mouse bone marrow-derived mononuclear phagocytes, J. Cell Biol. 97: 1113–1118.
Widmann, J. J., and Fahimi, H. D., 1975, Proliferation of mononuclear cells (Kupffer cells) and endothelial cells in regenerating rat liver. A light and electron microscopic cytochemical study, Am. J. Pathol. 80: 349–366.
Wisse, E., Van der Meulen, J., and Van’t Noordende, J. M., 1974, Kupffer cell reactions in rat liver under various conditions as observed in the electron microscope, J. Ultrastruct. Res. 46: 499–520.
Yamada, M., Naito, M., and Takahashi, K., 1990, Kupffer cell proliferation and glucan-induced granuloma formation in mice depleted of blood monocytes by strontium-89, J. Leukocyte Biol. 47: 195–205.
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© 1993 Springer Science+Business Media New York
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Ginsel, L.A. (1993). Origin of Macrophages. In: Horton, M.A. (eds) Macrophages and Related Cells. Blood Cell Biochemistry, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9534-9_3
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