Catalysis by Alcohol Dehydrogenases in Organic Solvents
Modern organic synthesis has been advanced in large part through an increased understanding of solvent effects and by the development of sophisticated reaction catalysts. However, some of the best-designed catalysts, i.e., naturally-occurring enzymes, have been generally excluded from use in organic synthesis because of their perceived requirement for a totally aqueous reaction solvent. Over recent years, reports documenting the ability of enzymes to function under nearly anhydrous conditions may reconcile this dilemma1–8 and lead to a significant expansion of the industrial applications of enzymes.
KeywordsOrganic Solvent Alcohol Dehydrogenase Carbonyl Compound Organic Medium Porous Glass
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