Effects of Glycerol-Induced Acute Renal Failure on Renal Phosphorus Handling
Previous studies have shown that fractional excretion of phosphorus (FE pi) is increased in rats that developed non-oliguric acute renal failure (ARF) close to 100% indicating that the bulk of filtered phosphorus was excreted in the urine. This finding differs significantly from the finding in rats with mercury chloride-induced oliguric ARF. In the latter, only about 1/4 of the filtered phosphorus reaches the urine, for an FEpi of about 25% (1). A similar finding has been seen also in humans with variable types of ARF (Carvounis, unpublished data).
KeywordsPhosphorus Glycerol Filtration Mercury Urea
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- 4.Scheinman, S.J. and Coulson, R.: Effect of perfusate phosphate concentration on responses to PTH in isolated rat kidney. Am. J. Physiol. 246:F907-F915, 1984.Google Scholar
- 5.Flamenbaum, W. , Gehr, M. , Gross, M. , Kaufman, J. , and Hamburger, R. In: Acute renal failure associated with myoglobinuria and hemoglobinuria; W.B. Saunders Co. , Phila. , 1983, pp 269–282.Google Scholar