The Plasma Lipoprotein System in Man
In the past decade there have been rapid advances in characterizing the plasma lipoproteins; their lipid and apoprotein content have been well defined, and their structure, including the nature of lipid-protein interactions have in part been identified. The metabolic relationships between the lipoproteins, their physiological roles and the regulation of their synthesis and degradation are the subjects of vigorous research. Some of this work suggests that the conventional, operational definitions of lipoproteins (very-low density, low density and high-density classes, VLDL, LDL and HDL, and chylomicrons) are no longer adequate to the components of this dynamically interrelated system. These names will however be retained in this review.
KeywordsCholesteryl Ester Lipoprotein Lipase Hepatic Lipase Familial Hypercholesterolaemia Extrahepatic Tissue
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