Lactose Malabsorption and Milk Consumption in Infants and Children

  • Emanuel Lebenthal
Part of the Nutrition and Food Science book series (NFS, volume 3)


There is controversy regarding malabsorption of lactose by the infant and child and the desirability of encouraging milk consumption in different age and ethnic groups. In the view of some investigators, research on lactose malabsorption is over-reported and over-interpreted.


Celiac Disease Lactase Deficiency Milk Consumption Tropical Sprue Lactase Activity 
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  1. 1.
    Mitchell JD, Brand J, Halbisch J: Weight-gain inhibition by lactose in Australian aboriginal children. Lancet 1: 500–502, 1977.CrossRefGoogle Scholar
  2. 2.
    Gray GM, Santiago NA: Intestinal β-galactosidases. I. Separation and characterization of three enzymes in normal human intestine. J Clin Invest 48: 716–728, 1969.CrossRefGoogle Scholar
  3. 3.
    Antonowicz I, Lebenthal E: Development pattern of samll intestinal enterokinase and disaccharidase activities in the human fetus. Gastroenterology 72: 1299–1303, 1977.Google Scholar
  4. 4.
    Kretchemer N: The geography and biology of lactose digestion and malabsorption. Postgrad Med J 53: 65–72, 1977.Google Scholar
  5. 5.
    Simoons FJ, Johnson JD, Kretchmer N: Perspective on milkdrinking and malabsorption of lactose. Pediatrics 59: 98–109, 1977.Google Scholar
  6. 6.
    Ransome-Kuti O, Kretchmer N, Johnson J, Gribble JT: A genetic study of lactose digestion in Nigerian families. Gastroenterology 68: 431–436, 1977.Google Scholar
  7. 7.
    Sahi T, Launiala K: More evidence for the recessive inheritance of selective adult type lactose malabsorption. Gastroenterology 73: 231–232, 1977Google Scholar
  8. 8.
    Lebenthal E, Tsuboi K, Kretchemer N: Characterization of human intestinal lactase and hetero-β-galactosidases of infants and adults. Gastroenterology 67: 1107–1113, 1974.Google Scholar
  9. 9.
    Freiburghaus AU, Schmitz J, Schindler M, Rotthauwe HW, Kuitunen P, Launiala K, Hadorn B: Protein patterns of brushborder fragments in congenital lactose malabsorption and in specific hypolactasia of the adult. N Engl J Med 294: 1030–1032, 1976.CrossRefGoogle Scholar
  10. 10.
    Lebenthal E, Antonowicz I, Shwachman H: Correlation of lactase activity, lactose tolerance and milk consumption in different age groups. Amer J Clin Nutr 28: 595–600, 1975.Google Scholar
  11. 11.
    Reddi V, Pershad J: Lactase deficiency in Indians. Amer J Clin Nutr 25: 114–119, 1972.Google Scholar
  12. 12.
    Johnson JD, Simoons FJ, Hurwitz R, Grange A, Sinatra FR, Sunshine P, Robertson WV, Bennett PH, Kretchmer N: Lactose malabsorption among adult Indians of the Great Basin and American Southwest. Amer J Clin Nutr 31: 381–387, 1978.Google Scholar
  13. 13.
    Lebenthal E: Small intestinal disaccharidase deficiencies. Pediat Clin N Amer 20: 757–766, 1975Google Scholar
  14. 14.
    Alpers D, Isselbacher K: Disaccharidase deficiency. Adv Metab Disord 4: 75–122, 1970.Google Scholar
  15. 15.
    Antonowicz I, Lebenthal E, Shwachman H: Disaccharidase activities in small intestinal mucosa in patients with cystic fibrosis. J Pediat 92: 214–219, 1978.CrossRefGoogle Scholar
  16. 16.
    Newcomer AD, McGill DB, Thomas RJ, Hofmann AF: Prospective comparison of indirect methods for detecting lactase deficiency. N Engl J Med 293: 1232–1236, 1975.CrossRefGoogle Scholar
  17. 17.
    Dahlqvist A: The basic aspects of the chemical background of lactase deficiency. Postgrad Med J 53: 57–64, 1977.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Emanuel Lebenthal
    • 1
  1. 1.Div. Gastroenterology Children’s Hosp. of BuffaloBuffaloUSA

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