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Syntheses and Biological Effects of Leukotrienes and Analogs

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Drugs Affecting Leukotrienes and Other Eicosanoid Pathways

Part of the book series: NATO ASI Series ((NSSA,volume 95))

Abstract

Polyunsaturated fatty acids such as arachidonic acid are transformed via the cyclooxygenase pathway into three groups of biological active compounds, the prostaglandin, the thromboxanes and the prostacyclins. These compounds are formed via the 5-Lipoxygenase pathway and play a major role as biolohical mediators on ommediate hypersensitivity reactions and inflammation 1–4.

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Author information

Authors and Affiliations

  1. Department of Chemistry, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA

    Bernd Spur & Wilfried Peters

  2. Department of Rheumatology and Immunology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, USA

    Bernd Spur

  3. Institut für Medizinische Mikrobiologie und Institut für Anorganische Chemie I, Universität Düsseldorf, D-4000, Düsseldorf 1, Germany

    Attilio Crea

Authors
  1. Bernd Spur
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  2. Attilio Crea
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  3. Wilfried Peters
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Editor information

Editors and Affiliations

  1. Karolinska Institute, Stockholm, Sweden

    B. Samuelsson

  2. University of Milan, Milan, Italy

    F. Berti  & G. C. Folco  & 

  3. University of Verona, Verona, Italy

    G. P. Velo

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© 1985 Plenum Press, New York

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Spur, B., Crea, A., Peters, W. (1985). Syntheses and Biological Effects of Leukotrienes and Analogs. In: Samuelsson, B., Berti, F., Folco, G.C., Velo, G.P. (eds) Drugs Affecting Leukotrienes and Other Eicosanoid Pathways. NATO ASI Series, vol 95. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7841-9_5

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  • DOI: https://doi.org/10.1007/978-1-4684-7841-9_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7843-3

  • Online ISBN: 978-1-4684-7841-9

  • eBook Packages: Springer Book Archive

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