Summary
The Vitamin E — Vitamin C synergestic effect towards peroxyl radicals has been characterized by Υ radiolysis in ethanolic medium. Vit E — Vit C aerated solutions have been irradiated in the presence or in the absence of dehydro-ascorbic acid for ratios (Vit E)/(Vit C) between 1 and 27. The experimental results point out that the regeneration of Vit E from its oxidised radical by Vitamin C (k = 6 x 105mol−1.dm3.s−1) may be in competition with its consumption through the reaction of dehydro-ascorbic acid with the tocopheroxyl radical (k = 2 x 107mol−1.dm3.s−1).
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References
L.A.Wittig, Vitamin E and lipid antioxidants in free radical initiated reactions, in Free radicals in Biology, Pryor, W.A., ed, Academic Press, New York, 4: 295 (1980).
G.W.Burton, A.Joyce and K.U.Ingold, Is Vitamin E the only lipid soluble chain breaking antioxidant in Human Blood plasma and erythrocyte membranes ?, Arch. Biochem. Biophys., 221: 281 (1983).
J.E.Packer, T.F.Slater and R.L.Willson, Direct observation of a free radical interaction between vitamin E and vitamin C, Nature, 278: 737 (1979).
M.G.Simic, Vitamin E radicals, in Oxygen and Oxy-Radicals in chemistry and biology, Rodgers, M.A.J. and Powers E.L.,eds, Academic Press, New York, 109 (1981).
D.Jore and C.Ferradini, Radiolytic study of d tocopherol in ethanolic solution, Febs. Lett., 183: 299 (1985).
D.Jore, L.K.Patterson and C.Ferradini, Pulse radiolytic study of o. tocopherol radical mechanisms in ethanolic solution, J. Free Rad. Biol. Med. 2: 405 (1986).
A.L.Tappel, Will antioxidant nutrients slow aging processes ?, Geriatrics, 23: 97 (1968).
P. B. McCay, Vitamin E: interactions with free radicals and ascorbate, Ann. Rev. Nutr., 5: 323 (1985).
M.Scarpa, A.Rigo, M.Maiorino, F.Ursini and C.Gregolin, Formation of octocopherol radical and recycling of oLtocopherol by ascorbate during peroxidation of phosphatidylcholine liposomes: an electron paramagnetic resonance study, Biochim. Biophys. Acta, 801: 215 (1984).
M.N.Kaouadji, D.Jore, L.K.Patterson and C.Ferradini, Radiolytic scanning of vitamin E -,vitamin C oxidation - reduction mechanisms, Bioelectrochem. Bioenerg., 18: 59 (1987).
G.R.Freeman, Radiation Chemistry of Ethanol, Nat. Stand. Ref. Data Serv., Nat. Bur. Stand. (U.S.) 48 (NSRDS-NBS 48), (1974).
D.Jore, N.Kaouadji and C.Ferradini, The Vitamin E — Vitamin C synergestic effect studied by X radiolysis in ethanol, presented at International Conference on medical, biochemical and chemical aspects of free radicals, IVth biennal general meeting of the Society for free radical research, Kyoto, April 9 to 13,(1988), (proceeding in press).
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© 1990 Plenum Press, New York
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Jore, D., Kaouadji, M.N., Ferradini, C. (1990). Vitamin E — Vitamin C Synergestic Effect Towards Peroxyl Radicals: Influence of Dehydro-Ascorbic Acid. In: de Paulet, A.C., Douste-Blazy, L., Paoletti, R. (eds) Free Radicals, Lipoproteins, and Membrane Lipids. NATO ASI Series, vol 189. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-7427-5_36
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DOI: https://doi.org/10.1007/978-1-4684-7427-5_36
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