Abstract
Fungalbionics implicates fungi/fungal metabolites as the cause of gout, hyperuricemia and their related diseases. These diseases are characterized by the presence of two distinctively different findings (detailed in Tables 1 and 2):
-
1.
Fungal-derived metabolites in extra-cellular compartments,
-
2.
Fungal structure/host immunoresponsive-type tissue lesions.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bourgeosis, C.H., Shank, R.C., Grossman, R.A, Johnson, D.O., Wooding, W.L., and Chandavimol, P., 1971, Acute aflatoxin Bl toxicity in the macaque, Lab Invest., 24: 206.
Edozien, J.C., Udo, U., Young, V.R., and Scrimshaw, N.S., 1970, Effects of high levels of yeast feeding on uric acid metabolism of young men, Nature, 228: 180.
Eigsti, O.J. and Dustin, P., 1955, Colchicine in Agriculture and Medicine, Iowa State College Press, Ames, Iowa.
Gratzl, E., 1968, Spezielle Pathologie und Therapie der Geflugel krankheiten, Ferdinand Enke Verlag, Stuttgart.
Hasselbacher, P. and Schumacher, H.R., 1978, Immunoglobulin in tophi and on the surface of monosodium urate crystals, Arth. Rheum., 21: 353.
Jarmai, 1925, Durch schimmeligen Mais verusachte Gicht bei Gausen, Deutsche tierarzil Wchnschr., 33: 580.
Kubena, L.F., Phillips, T.D., Creger, C.R., Witzel D.A., and Heidelbaugh, N.D., 1983, Toxicity of Ochratoxin A and tannic acid to growing chicks. Poultry Science, 62: 1786.
Kurrien F., Green G.H., and Rowles S.L., 1975, Localized deposition of calcium oxalate around a pulmonary Aspergillus niger fungus ball, Am. J. Clin. Pathol., 64: 556.
Lindsay, J., 1913, Gout-Its Etiology, Pathology and Treatment, Oxford University Press, London.
Manning, R.O., Wyatt, R.D., 1984, Comparative toxicity of Chaetomium contaminated corn and various chemical forms of oosporein in broiler chicks, Poultry Science, 63: 251.
Marinello, E., Riario-Sforza, G., Marcolongo, R., 1985, Plasma follicle-stimulating hormone, luteinizing hormone, and sex hormones in patients with gout, Arth. Rheum., 28(2): 127.
Muller, J., 1988, (Personal communication) Director, Mycology Laboratory, Univ. of Freiburg, Freiburg, West Germany.
Peckham, J.C., Doupnik, B., and Jones, O., 1971, Acute toxicity of Ochratoxins A and B in chicks, Appl Microbiol., 21: 492.
Pegram, R.A., Wyatt, R.D., and Smith, T.L., 1982, Oosporein-toxicosis in the turkey poult, Avian Diseases, 26: 476.
Pegram, R.A., and Wyatt, R.D., 1981, Avian gout caused by oosporein, a mycotoxin produced by Chaetomium trilaterale, Poult. Sci., 60: 2429.
Roush, A.H., 1961, Crystallization of purines in the vacuole of Candida utilis, Nature, 190: 449.
Sherman, M.S., 1946, Pathologic Changes in Gouty Arthritis, Arch. Path., 42: 557.
Siller, W.G., 1959, Avian nephritis and visceral gout, Lab. Invest., 8: 1319.
Slonim, R.R., Howell, D.S. and Brown, H.E., 1962, Influence of griseofulvin on acute gouty arthritis. Arth Rheum., 5: 397.
Smego, R.A. Jr., 1984, In vitro susceptibility of Naegleria fowleri to ketoconazole, BAYn7133, and allopurinol riboside. J. Parasitol. 70(2): 317.
Sommers, S.C., and Churg, J., 1982, Kidney pathology in hyperur-icemia and gout, in Yu, T. and Burger, L., (eds), The Kidney in Gout and Hyperuricemia, Futura, New York.
Sparagana, M., and Phillips, G., 1972, Dehydroepiandrosterone metabolism in gout, Steroids, 19: 477.
Talbott, J.H., 1964, Gout, Grune and Stratton, New York-London.
Valentini, U., Riario-Sforza, G., Marcolongo, R., and Marinello, E., 1980, Hormonal aspects of gout patients, in Purine Metabolism in Man-III: Clinical and Therapeutic Aspects, Rapado, A., Watts, R.W.E., and De Bruyn C.H.M.M., (eds), Plenum Press, New York and London.
Weete, J.D., and Weber D.J., 1980, Lipid Biochemistry of Fungi and Other Organisms, Plenum Press, New York And London.
Wells, H.G., 1914, Chemical Pathology, W.B. Saunders Co., Philadelphia & London.
Wolfson, W.Q., Guterman, H.S., Levine, R., Cohn, C., Hunt, H.D., and Rosenberg, E.F., 1949, An endocrine finding apparently characteristic of gout, J. Clin. Endocr., 9: 497.
Wyngaarden, J.B. and Kelley, W.N., 1976, Gout and Hyperuricemia, Grune and Stratton, New York.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Plenum Press, New York
About this chapter
Cite this chapter
Costantini, A.V. (1989). Fungalbionics: A New Concept of the Etiology of Gout, Hyperuricemia and their Related Diseases. In: Mikanagi, K., Nishioka, K., Kelley, W.N. (eds) Purine and Pyrimidine Metabolism in Man VI. Advances in Experimental Medicine and Biology, vol 253A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5673-8_44
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5673-8_44
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5675-2
Online ISBN: 978-1-4684-5673-8
eBook Packages: Springer Book Archive