Introduction to Session on the Pathophysiology of Breathing Control and Breathing: Awake and Asleep

  • N. S. Cherniack
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 393)


From a modelling perspective the respiratory system is often considered to function as two interactive parts. First, there is a controller made up of chemoreceptors and the respiratory neurones in the pons and the medulla which acts on the second part, the respiratory plant which consists of the lung, the respiratory muscles, and the body tissues connected to the lung by the circulation. The assumption is made that ventilation is regulated so as to keep arterial levels of PCO2 and PO2 constant. Over the years this basic concept has been amplified with more elements included in the model.


Respiratory System Respiratory Muscle Sleep Stage Respiratory Plant Respiratory Neurone 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • N. S. Cherniack
    • 1
  1. 1.Case Western Reserve University School of MedicineClevelandUSA

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