Introduction to Session on the Pathophysiology of Breathing Control and Breathing: Awake and Asleep

Abstract

From a modelling perspective the respiratory system is often considered to function as two interactive parts. First, there is a controller made up of chemoreceptors and the respiratory neurones in the pons and the medulla which acts on the second part, the respiratory plant which consists of the lung, the respiratory muscles, and the body tissues connected to the lung by the circulation. The assumption is made that ventilation is regulated so as to keep arterial levels of PCO₂ and PO₂ constant. Over the years this basic concept has been amplified with more elements included in the model.