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A New Method for Detecting Lipid Peroxidation by Using Dye Sensitized Chemiluminescence

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Free Radicals in Diagnostic Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 366))

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Abstract

It has been suggested that iron induced-microsomal lipid peroxidation produces at least two excited species; one for 1O2, and another for excited carbonyl(s), via splitting of a dimer of lipid peroxy radicals1. The carbonyls in excited triplet state are known to transfer their excitation energy to triplet sensitizers such as rose-bengal, eosin and 9:10-dibromoanthracene which have suitable molecular orbitals.

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References

  1. K. Sugioka and M. Nakano, A possible mechanism of the generation of singlet molecular oxygen in NADPH-dependent microsomal lipid peroxidation. Biochim Biophys Acta 423:203 (1976).

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© 1994 Springer Science+Business Media New York

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Hiramitsu, T., Arimoto, T., Ito, T., Nakano, M. (1994). A New Method for Detecting Lipid Peroxidation by Using Dye Sensitized Chemiluminescence. In: Armstrong, D. (eds) Free Radicals in Diagnostic Medicine. Advances in Experimental Medicine and Biology, vol 366. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1833-4_28

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  • DOI: https://doi.org/10.1007/978-1-4615-1833-4_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5742-1

  • Online ISBN: 978-1-4615-1833-4

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