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Free Radicals in Diagnostic Medicine

A Systems Approach to Laboratory Technology, Clinical Correlations, and Antioxidant Therapy

  • Donald Armstrong

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 366)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Pathophysiology and Analysis

  3. Organ Specific Disorders

    1. Robert E. Anderson, Frank L. Kretzer, Laurence M. Rapp
      Pages 73-86
    2. Alice P. Pentland
      Pages 87-97
    3. Daniel J. Brackett, Paul B. McCay
      Pages 147-163
    4. Wayne R. Waz, Leonard G. Feld
      Pages 171-183
    5. Eve de Lamirande, Claude Gagnon
      Pages 185-197
  4. Systemic Involvement

    1. Jonathan A. Leff
      Pages 199-213
    2. Peter J. O’Brien
      Pages 215-239
    3. Stephen M. Hahn, C. Murali Krishna, James B. Mitchell
      Pages 241-251
    4. Patricia A. Abello, Timothy G. Buchman, Gregory B. Bulkley
      Pages 253-268
    5. Harold H. Draper, William J. Bettger
      Pages 269-289

About this book

Introduction

An International Syaposiua on Free Radicals in Diagnostic Medicine was co-sponsored by the state University of New York at Buffalo, Roswell Park Cancer Institute, and the Upstate NY Section of the American Association of Clinical Chemistry. The theme was "A Systems Approach To Laboratory Technology, Clinical Correlations And Antioxidant Therapy." The symposium was held on October 7-8, 1993 at the Hyatt Hotel and on October 9 at Roswell Park Cancer Institute, Buffalo, New York. This proceedings volume contains chapters from platform presentations, poster sessions and from invited special lectures in the areas of basic science, clinical applications and efficacy of treatment. A Special Lecture on the relevance of free radical analysis to clinical medicine was presented by Professor Kunio Yagi of Japan. The Yagi procedure to measure thiobarbituric acid (TBA) reaction reflects the amount of reactive substances, lipid peroxides and aldehydes, in the sample. For example, normal subjects will have less than 4 nmol/ml of serum lipid peroxides, while a person with diabetes generally has equal or greater than 5.0 and a diabetic person with vascular complications often exceeds 7.5 nmol/ml. Serum TBA is a clinically important measure that relates to aging, gender and estrogen as an antioxidant, in the prognosis for vascular disorders, and in pathological conditions relative to the amount of lipid peroxidation. The BASIC SCIENCES portion of the program examined: "Mechanisms of Action, Pathophysiology and Laboratory Tests" in six presentations.

Keywords

Lipid Oxidation antioxidant cancer chemistry lipide pathophysiology physiology research

Editors and affiliations

  • Donald Armstrong
    • 1
  1. 1.State University of New York at BuffaloBuffaloUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-1833-4
  • Copyright Information Plenum Press, New York 1994
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5742-1
  • Online ISBN 978-1-4615-1833-4
  • Series Print ISSN 0065-2598
  • Buy this book on publisher's site
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