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Brief Communication Carcino-Embryonic Antigen (CEA) in Nasopharyngeal Carcinoma and Chronic Nasopharyngitis

  • Yuin Yin Shen
  • Pei Sheng Huang
Part of the Developments in Medical Virology book series (DIMV, volume 1)

Abstract

When carcino-embryonic antigen (CEA) was discovered in carcinoma of the colon and fetal colon mucosa (Gold and Friedman, 1965), it was thought to be a specific antigen and also a specific marker of human digestive system and its carcinomas. Since then, additional case reports indicated that CEA was also present in carcinoma of various organs such as lung, breast, ovary, uterine cervix, and urinary bladder. Thus far no report has evaluated the nasopharynx, where EBV appears to replicate, or nasopharyngeal carcinoma, which is suspected of being caused by EBV. With the use of the immunoperoxidase method, the presence and the distribution of CEA in nasopharyngeal epithelium in relation to inflammation and carcinomatous change were studied in our laboratory.

Keywords

Nasopharyngeal Carcinoma Nasopharyngeal Epithelium Human Digestive System Additional Case Report Carcinomatous Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Gold, P. and Friedman, S.O. Specific carcinoembryonic antigen of the human digestive system. J. Exp. Med. 122: 467–481 (1965).PubMedCrossRefGoogle Scholar
  2. Goldenberg, D.M. Immunocytochemical detection of carcino¬embryonic antigen in conventional histopathology specimens. Cancer 42: 1546–1553 (1978).PubMedCrossRefGoogle Scholar
  3. Jautzke, G., etal. Immunohistochemical demonstration of carcinoembryonic antigen (CEA) and its correlation with grading and staging on tissue sections of urinary bladder carcinoma. Cancer 50: 2050–2056 (1982).CrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • Yuin Yin Shen
    • 1
  • Pei Sheng Huang
    • 1
  1. 1.Department of Anatomical PathologyFujian Medical CollegeFuzhou, FujianPeople’s Republic of China

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