Abstract
Disorders of membrane function in the gastrointestinal tract are frequent and cause significant morbidity and mortality. In the developed nations, diarrheal disease is a cause of loss of productivity at work, and death of neonatal livestock; thus, it is primarily of economic significance. However, in the Third World, diarrheal diseases account for the deaths of over 5 million infants and young children each year. Whereas such economic or social issues might direct the investigator to the gastrointestinal tract, its easy accessibility is perhaps the main reason why such research has flourished. As a result, studies of gastrointestinal tissue have added much to our understanding of mechanisms of transport in all epithelia.
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Powell, D.W. (1986). Ion and Water Transport in the Intestine. In: Andreoli, T.E., Hoffman, J.F., Fanestil, D.D., Schultz, S.G. (eds) Physiology of Membrane Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2097-5_33
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