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Canrenone Prevents Na,K Pump Inhibition Induced by Volume Expansion in Normal Subjects

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Diuretics: Basic, Pharmacological, and Clinical Aspects

Part of the book series: Developments in Nephrology ((DINE,volume 18))

Abstract

Canrenone is the main active metabolite of the diuretic and antihypertensive drugs spironolactone and K-canrenoate (1), end competes with aldosterone for a common cytosolic receptor in distal and collecting tubules of the nephron (2).

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References

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Author information

Authors and Affiliations

  1. Divisioni di Nefrologia e Dialisi, Ospedale S. Giovanni Battista, Torino, Italy

    R. Boero (Cattedra di Nefrologia Medica dell’Universtità di Torino), C. Guarena, F. Quarello, C. Rosati, B. Rolando, M. C. Deabate & G. Piccoli

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  1. R. Boero
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  2. C. Guarena
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  3. F. Quarello
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  4. C. Rosati
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  5. B. Rolando
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  6. M. C. Deabate
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  7. G. Piccoli
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Editor information

Editors and Affiliations

  1. Department of Nephrology, University of Naples, Naples, Italy

    V. E. Andreucci M.D.  & Antonio Dal Canton M.D.  & 

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© 1987 Martinus Nijhoff Publishing, Boston

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Boero, R. et al. (1987). Canrenone Prevents Na,K Pump Inhibition Induced by Volume Expansion in Normal Subjects. In: Andreucci, V.E., Dal Canton, A. (eds) Diuretics: Basic, Pharmacological, and Clinical Aspects. Developments in Nephrology, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2067-8_12

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  • DOI: https://doi.org/10.1007/978-1-4613-2067-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9227-2

  • Online ISBN: 978-1-4613-2067-8

  • eBook Packages: Springer Book Archive

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