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Origin and Significance of Transplantation Antigens Induced on Cells Transformed by UV Radiation

  • Chapter
Development and Recognition of the Transformed Cell

Abstract

Many experimentally induced cancers express cell surface antigens not normally found on the tissue of origin. Some of these antigens induce complete or partial protection against a lethal challenge with the tumor cells. Because of their ability to induce resistance to tumor transplantation, they have been termed tumor-specific transplantation antigens (TSTA), and they are defined primarily on the basis of their ability to induce a protective immune response in vivo.

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  1. Department of Immunology, University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, Texas, 77030, USA

    Lisa W. Hostetler & Margaret L. Kripke

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  1. Lisa W. Hostetler
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  2. Margaret L. Kripke
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Editors and Affiliations

  1. Division of Immunology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, 19104-6082, USA

    Mark I. Greene

  2. Department of Oncogenesis, Institute for Cancer Research, Osaka University Medical School, Osaka, 553, Japan

    Toshiyuki Hamaoka

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© 1987 Plenum Press, New York

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Hostetler, L.W., Kripke, M.L. (1987). Origin and Significance of Transplantation Antigens Induced on Cells Transformed by UV Radiation. In: Greene, M.I., Hamaoka, T. (eds) Development and Recognition of the Transformed Cell. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1925-2_20

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  • DOI: https://doi.org/10.1007/978-1-4613-1925-2_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9070-4

  • Online ISBN: 978-1-4613-1925-2

  • eBook Packages: Springer Book Archive

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