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Development and Recognition of the Transformed Cell

  • Book
  • © 1987

Overview

Editors:
  1. Mark I. Greene

    1. Division of Immunology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA

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  2. Toshiyuki Hamaoka

    1. Department of Oncogenesis, Institute for Cancer Research, Osaka University Medical School, Osaka, Japan

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Cytogenetics of Neoplasia

    • Peter C. Nowell, Carlo M. Croce
    Pages 1-19

  3. The Structure and Function of the Normal c-myc Gene and Its Alteration in Malignant Cells

    • Rebecca A. Taub
    Pages 21-37

  4. Protooncogene Expression in Lymphoid Cells

    • John C. Reed
    Pages 39-58

  5. Oncogene Products as Receptors

    • Erica M. S. Sibinga, Gail R. Massey, Mark I. Greene
    Pages 59-67

  6. Monoclonal Antibodies Reactive with the neu Oncogene Product Inhibit the Neoplastic Properties of neu-Transformed Cells

    • Jeffrey A. Drebin, Victoria C. Link, Mark I. Greene
    Pages 69-80

  7. Relationship of the c-fms Protooncogene Product to the CSF-1 Receptor

    • Charles J. Sherr
    Pages 81-91

  8. Two erbB-Related Protooncogenes Encoding Growth Factor Receptors

    • Tadashi Yamamoto, Kumao Toyoshima
    Pages 93-110

  9. The Receptor for Epidermal Growth Factor

    • Wendelyn H. Inman, Graham Carpenter
    Pages 111-121

  10. The Role of the abl Gene in Transformation

    • Naomi Rosenberg
    Pages 123-144

  11. Comparison of the Structural and Functional Properties of the Viral and Cellular src Gene Products

    • Paul Coussens, Joan S. Brugge
    Pages 145-156

  12. Protein Kinase C as the Site of Action of the Phorbol Ester Tumor Promoters

    • Marie L. Dell’Aquila, Barbour S. Warren, David J. De Vries, Peter M. Blumberg
    Pages 157-185

  13. Involvement of Human Retrovirus in Specific T-Cell Leukemia

    • Mitsuaki Yoshida, Motoharu Seiki, Junichi Fujisawa, Junichiro Inoue
    Pages 187-202

  14. Mechanisms of Virus-Induced Alterations of Expression of Class I Genes and Their Role on Tumorigenesis

    • Daniel Meruelo
    Pages 203-220

  15. Antigenic Requirements for the Recognition of Moloney Murine Leukemia Virus-Induced Tumors by Cytotoxic T Lymphocytes

    • David C. Flyer, Douglas V. Faller, Steven J. Burakoff
    Pages 221-230

  16. SV40 Tumor Antigen

    • Satvir S. Tevethia, Janet S. Butel
    Pages 231-242

  17. Correlation of Natural Killer Cell Recognition with ras Oncogene Expression

    • Paul W. Johnson, William S. Trimble, Nobumichi Hozumi, John C. Roder, Anthony J. Pawson
    Pages 243-259

  18. A Regulatory Role of Natural Killer Cells (LGL) in T-Cell-Mediated Immune Response

    • Katsuo Kumagai, Ryuji Suzuki, Satsuki Suzuki, Tetsu Takahashi, Minoru Igarashi
    Pages 261-277

  19. Immune Regulation in Neoplasia

    • J. Kevin Steele, Agnes Chan, Anthea T. Stammers, Julia G. Levy, Rakesh Singhai
    Pages 279-293

  20. The Generation and Down-Regulation of the Immune Response to Progressive Tumors

    • Robert J. North, Antonio DiGiacomo, Earl S. Dye
    Pages 295-305
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Keywords

About this book

The study of the phenotypic and genetic features that characterize the malignant cell is a rapidly growing and changing field. Clearly new insights into the processes involved in normal and abnormal cell growth will facilitate our understanding of events relevant to cancer and cellular differentiation. Early studies on genetic fea­ tures associated with cancer focused on chromosomal abnormalities that were observable in several human malignancies. The more recent examination of onco­ genes and the proteins they encode has helped pinpoint many steps in different processes that might be involved in cancer. Immunologic studies of cancer have also developed from an imprecise series of investigations to a more detailed molecular examination of cell-surface struc­ tures that can be recognized immunologically. In the course of the development of modern tumor immunology, it has become clear that many of the antigens that can be recognized appear to be the products of genes involved in cell growth. Fur­ thermore, changes in the cell surface of malignant cells have often been found to include alteration of nonprotein constituents.

Editors and Affiliations

  • Division of Immunology, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA

    Mark I. Greene

  • Department of Oncogenesis, Institute for Cancer Research, Osaka University Medical School, Osaka, Japan

    Toshiyuki Hamaoka

Bibliographic Information

  • Book Title: Development and Recognition of the Transformed Cell

  • Editors: Mark I. Greene, Toshiyuki Hamaoka

  • DOI: https://doi.org/10.1007/978-1-4613-1925-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1987

  • Softcover ISBN: 978-1-4612-9070-4Published: 01 November 2011

  • eBook ISBN: 978-1-4613-1925-2Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XVI, 476

  • Number of Illustrations: 39 b/w illustrations

  • Topics: Oncology, Animal Anatomy / Morphology / Histology, Plant Sciences

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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