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Unfolding Perspectives on the Genetic Effects of Human Exposures to Radiation

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DNA Damage and Repair in Human Tissues

Part of the book series: Basic Life Sciences ((BLSC,volume 53))

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Abstract

My role in this program is to present the current status of the longrunning studies on the potential genetic effects of the atomic bombs, and then indicate the direction of current thinking regarding future studies on this subject, with particular reference to studies at the DNA level. I would like to begin, however, with what will seem like a diversion, a brief review of the results of some rather recent, seemingly unrelated studies which, I believe, point to the kinds of fundamental biases which may inadvertently creep into studies of spontaneous and induced mutation rates. Such biases could be very relevant to the apparent discrepancy between the results in Japan and the experimental observations on mice, to which I will speak briefly, and should be avoided in planning for any future studies.

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© 1990 Plenum Press, New York

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Neel, J.V. (1990). Unfolding Perspectives on the Genetic Effects of Human Exposures to Radiation. In: Sutherland, B.M., Woodhead, A.D. (eds) DNA Damage and Repair in Human Tissues. Basic Life Sciences, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0637-5_27

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  • DOI: https://doi.org/10.1007/978-1-4613-0637-5_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7903-7

  • Online ISBN: 978-1-4613-0637-5

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