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Possible Interference of Uric Acid in the Measurement of Catecholamines by HPLC with Electrochemical Detection

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Neuropsychopharmacology of the Trace Amines

Abstract

It has been reported that selective detection of catecholamines and indoleamines by differential pulse voltammetry “in vivo” may be contaminated by the simultaneous detection of uric acid (Crespi et al., 1983; O’Neill et al., 1984). In addition uric acid has been identified in striatal and nucleus accumbens perfusates (Ungerstedt, 1984) and brain extracts (Aoki et al., 1984) by mean of HPLC-ED. The present report addresses the possibility that uric acid may interfere in the analysis of catecholamines in brain and spinal cord extracts by mean of HPLC-ED.

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References

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© 1985 The Humana Press Inc.

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Weil-Fugazza, J., Godefroy, F. (1985). Possible Interference of Uric Acid in the Measurement of Catecholamines by HPLC with Electrochemical Detection. In: Boulton, A.A., Maitre, L., Bieck, P.R., Riederer, P. (eds) Neuropsychopharmacology of the Trace Amines. Humana Press. https://doi.org/10.1007/978-1-4612-5010-4_33

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  • DOI: https://doi.org/10.1007/978-1-4612-5010-4_33

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9397-2

  • Online ISBN: 978-1-4612-5010-4

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