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Elements of Cutaneous Embryology, Anatomy, and Biochemistry

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Dermatopathology
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Abstract

The youngest human embryos in which cutaneous development was observed were about 4–5 weeks old. At that point, the embryo’s external surface is covered by the ectoderm, a monolayer of cells stretching over a mesenchymal mantle. It is partially overlaid by the “periderm,” a second layer of bulky elements endowed with microvilli. This situation and ensuing events are presented in Fig. 1.1.

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References

  1. Montagna W, Parakkal PF. The structure and function of skin. 3rd ed. New York: Academic; 1974. p. 75–95.

    Google Scholar 

  2. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 9–21.

    Google Scholar 

  3. Odland GF. In: Goldsmith LA, editors. Physiology, biochemistry, and molecular biology of the skin, 2nd ed. New York: Oxford University Press; 1991. p. 3–5.

    Google Scholar 

  4. Hib J. Histologia de Di Fiore. Buenos Aires: El Ateneo; 2001. p. 171.

    Google Scholar 

  5. James WD, Berger TG, Elston DM, editors. Andrews’ diseases of the skin. 10th ed. Philadelphia: W.B. Saunders Elsevier; 2006. p. 1.

    Google Scholar 

  6. Montagna W, Parakkal PF. The structure and function of skin. 3rd ed. New York: Academic; 1974. p. 48.

    Google Scholar 

  7. Steinert PM, Freedberg IM. In: Goldsmith LA, editors. Physiology, biochemistry, and molecular biology of the skin, 2nd ed. New York: Oxford University Press; 1991. p. 113–41.

    Google Scholar 

  8. De Robertis EMF, Hib J. Fundamentos de biologia celular y molecular de De Robertis. 3rd ed. Buenos Aires: El Ateneo; 2001. p. 80–1.

    Google Scholar 

  9. James WD, Berger TG, Elston DM, editors. Andrews’ diseases of the skin. 10th ed. Philadelphia: W.B. Saunders Elsevier; 2006. p. 3.

    Google Scholar 

  10. Resing KA, Dale Ba. In: Goldsmith LA, editors. Physiology, biochemistry, and molecular biology of the skin, 2nd ed. Oxford: Oxford University Press; 1991. p. 148–62.

    Google Scholar 

  11. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 851.

    Google Scholar 

  12. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 30.

    Google Scholar 

  13. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 15.

    Google Scholar 

  14. Montagna W, Parakkal PF. The structure and function of skin. 3rd ed. New York: Academic; 1974. p. 18.

    Google Scholar 

  15. Montagna W, Parakkal PF. The structure and function of skin. 3rd ed. New York: Academic; 1974. p. 24.

    Google Scholar 

  16. De Robertis EMF, Hib J, Ponzio R. Biologia celular y molecular de De Robertis. 15th ed. Buenos Aires: El Ateneo; 2010. p. 162–3.

    Google Scholar 

  17. Elder DE, et al., editors. Lever’s histopathology of the skin, 9th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 9.

    Google Scholar 

  18. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 858.

    Google Scholar 

  19. Zelickson AS. In: Zelickson AS, editors. Ultrastructure or normal and abnormal skin. Philadelphia: Lea & Febiger; 1967, p. 163.

    Google Scholar 

  20. Rosai J. Rosai and Ackerman’s surgical pathology. 9th ed. Edinburgh: Mosby; 2006. p. 154.

    Google Scholar 

  21. Leider M, Rosenblum MA. A dictionary of medical words, terms and phrases. West Haven: Dome Laboratory; 1976. p. 297.

    Google Scholar 

  22. Unna PG. Histopathologie der Hautkrankheiten. Berlin: A. Hirschwald Verlag; 1894. p. 1148.

    Google Scholar 

  23. Magana Garcia M, Ackerman AB. Naming acquired melanocytic nevi. Am J Dermatopathol. 1990;12(1):193–209.

    Article  PubMed  Google Scholar 

  24. Mehregan AH, Hashimoto K, editors. Pinkus’s guide to dermatohistopathology. 5th ed. Norwalk: Appleton-Lange; 1991. p. 444.

    Google Scholar 

  25. Montagna W, Parakkal PF. The structure and function of skin. 3rd ed. New York: Academic; 1974. p. 89.

    Google Scholar 

  26. Mehregan AH, Hashimoto K, editors. Pinkus’s guide to dermatohistopathology. 5th ed. Norwalk: Appleton-Lange; 1991. p. 39.

    Google Scholar 

  27. Mescher AL, editor. Junqueira’s basic histology. 12th ed. New York: McGraw Hill; 2010. p. 233.

    Google Scholar 

  28. De Robertis EMF, Hib J. Fundamentos de biologia celular y molecular de De Robertis. 3rd ed. Buenos Aires: El Ateneo; 2001. p. 113–4.

    Google Scholar 

  29. Mescher AL, editor. Junqueira’s basic histology. 12th ed. New York: McGraw Hill; 2010. p. 96.

    Google Scholar 

  30. Uitto J, Fazio H, Bashir H, Rosenbloon J. In: Goldsmith LA, editor. Physiology, biochemistry, and molecular biology of the skin, 2nd ed. New York: Oxford University Press; 1991, p. 530.

    Google Scholar 

  31. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 11.

    Google Scholar 

  32. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 28.

    Google Scholar 

  33. Mehregan AH, Hashimoto K, editors. Pinkus’s guide to dermatohistopathology. 5th ed. Norwalk: Appleton-Lange; 1991. p. 27.

    Google Scholar 

  34. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 27.

    Google Scholar 

  35. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th ed. Philadelphia: J.B. Lippincott; 1990. p. 24.

    Google Scholar 

  36. Enzinger FM, Weiss SW. Soft tissue tumors. 3rd ed. St. Louis: Mosby; 1995. p. 703–4.

    Google Scholar 

  37. Scheithauer BW, Woodruff JM, Erlandson RA. In: Rosai J, editors. Atlas of tumor pathology, 3rd series, Fascicle 24. Washington, D.C.: Armed Forces Institute of Pathology; 1999, p. 1–15.

    Google Scholar 

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Zappi, E., Zappi, E.A. (2013). Elements of Cutaneous Embryology, Anatomy, and Biochemistry. In: Dermatopathology. Springer, London. https://doi.org/10.1007/978-1-4471-2894-6_1

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  • DOI: https://doi.org/10.1007/978-1-4471-2894-6_1

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