Abstract
Very low-calorie diets (VLCDs) have courted controversy since their invention in the 1920s, when the original “last chance diet” seemed to cause premature young deaths due to an elongation of the QT interval. VLCDs, which induce a mild clinically benign ketosis, are second only to bariatric surgery in achieving substantial weight loss, even in the presence of diabetes. VLCDs are now standardized and nutritionally complete, providing everything required including trace elements and minerals. Not suitable for everyone, with a careful choice of patient, they are now deemed to be a safe and effective diet as long as they are administered under close medical supervision.
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References
Hamzelou J. Global health report card. New Sci. 2012;216(2896–2897):6–7.
Kopelman P. Health risks associated with overweight and obesity. Obes Rev. 2007;8:13–7.
Slade C. Diabetes-weight management. Ashtead/Surrey: Global Business Media Ltd; 2012.
Haslam D. Obesity co-morbidities and the obesity paradox. Pract Diabetes. 2013;30(3):132–5.
National Audit Office. Tackling obesity in England; report by the comptroller and auditor general. London: The Stationery Office; 2001.
Puhl R, Bownell K. Bias, discrimination and obesity. Obes Res. 2001;9(12):788–805.
NICE. Obesity; Guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children. 2006. Report No.: NICE clinical guideline 43.
Truby H, Baic S, deLooy A. Randomised control trial of four commercial weight loss programs in the UK; initial findings from the BBC diet trials. BMJ. 2006;332(7553):1309–14.
Lahmann C, Henrich G, Henningsen P, Baessler A, Fischer M, Loew T, et al. The impact of personality traits on the success of a multimodal obesity treatment. Behav Med. 2011;37(4):119–24.
Hallam CL, Broom J, Mullins G, Cook D, Haslam D. Comparison of weight loss in patients with type 2 diabetes using a very-low-calorie diet (VLCD) approach. Poster presentation European Congress on Obesity. May 2012.
Mullins G, Hallam CL, Broom J. Ketosis, keto-acidosis and very low calorie diets; putting the record straight. Nutr Bull. 2011;36(3):397–402.
Saris W. VLCD and sustained weight loss. Obes Res. 2001;9 Suppl 4:295S–301.
Evans FaS J. A departure from usual methods in treating obesity. Am J Med Sci. 1929;177:339–48.
Bray G. The battle of the bulge; a history of obesity research. Pittsburgh: Dorrance publishing; 2007.
DOM UK. Position statement on very low energy diets in the management of obesity. 2007. Available from: http://www.domuk.org/files/very-low-energy-diets.pdf.
Team TE. EndNote for iPad getting started guide. New York: Thomson Reuters; 2013.
Tsai AG, Wadden TA. The evolution of very-low-calorie diets: an update and meta-analysis. Obesity. 2006;14(8):1283–93.
Baker S, Jerums G, Proietto J. Effects and clinical potential of very-low-calorie diets (VLCDs) in type 2 diabetes. Diabetes Res Clin Pract. 2009;85(3):235–42.
Yip I, Go V, Desheilds S, Saltsman P, Bellman M, Thames G, et al. Liquid meal replacements and glycaemic control in obese type two diabetes patients. Obes Res. 2001;9(S4):341–7.
Snel MaS M. Quality of life in type 2 diabetes mellitus after a very low calorie diet and exercise. Eur J Intern Med. 2012;23:143–9.
Eastman Q. Very low calorie diets make adipocytes scream. J Proteome Res. 2009;8(12):5408.
Williams EB. Can very low calorie diets increase life expectancy? Br Nutr Found Nutr Bull. 2010;35:152–6.
http://www.people.com/people/archive/article/0,,20069895,00.html. Accessed 24 Apr 2013.
Isner JM, Sours HE, Paris AL, Ferrans VJ, Roberts WC. Sudden, unexpected death in avid dieters using the liquid-protein-modified-fast diet. Observations in 17 patients and the role of the prolonged QT interval. Circulation. 1979;60:1401–12.
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Cook, D.R.J. (2014). Very Low-Calorie Diets: Saint or Sinner?. In: Haslam, D., Sharma, A., le Roux, C. (eds) Controversies in Obesity. Springer, London. https://doi.org/10.1007/978-1-4471-2834-2_21
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DOI: https://doi.org/10.1007/978-1-4471-2834-2_21
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