Liver Cancer pp 137-144 | Cite as

Screening with Ultrasonography of Patients at High-Risk for Hepatocellular Carcinoma: Thrombocytopenia as a Valid Surrogate of Cirrhosis

  • Sheng-Nan Lu
  • Jing-Houng Wang
  • Kwong-Ming Kee
  • Po-Lin Tseng
Part of the Methods of Cancer Diagnosis, Therapy and Prognosis book series (HAYAT, volume 5)

Sequelae of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, including hepatocellular carcinoma (HCC), liver cirrhosis (LC) and their complications, are health burdens of the world. Improving treatment results for early stage HCC makes the screening meaningful. Two-staged HCC screening identifying high risk subjects in the first stage and screening for HCC by ultrasonography (US) in the second stage is a practical and workable concept. The benefit of US screening on high risk groups has been well documented, but “who should be included in the US screening” depends on cost-benefits and considerations of feasibility.


Liver Fibrosis Viral Liver Disease Forns Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media B.V. 2009

Authors and Affiliations

  • Sheng-Nan Lu
    • 1
  • Jing-Houng Wang
    • 1
  • Kwong-Ming Kee
    • 1
  • Po-Lin Tseng
    • 1
  1. 1.Division of Hepatogastroenterology, Department of Internal MedicineKaohsiung Chang Gung Memorial HospitalNiaosungTaiwan

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