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Diseases associated with altered ryanodine receptor activity

  • Chapter
Calcium Signalling and Disease

Part of the book series: Subcellular Biochemistry ((SCBI,volume 45))

Abstract

Mutations in two intracellular Ca2+ release channels or ryanodine receptors (RyR1 and RyR2) are associated with a number of human skeletal and cardiac diseases. This chapter discusses these diseases in terms of known mechanisms, controversies, and unanswered questions. We also compare the cardiac and skeletal muscle diseases to explore common mechanisms

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Authors and Affiliations

  1. Department of Molecular Physiology and Biophysics, University of lowa 5-660 Bowen science Building 51 Newton Road, Lowa, IA 52242, U.S

    W.J. DURHAM, X.H.T. WEHRENS, S. SOOD & S.L. HAMILTON

  2. Department of Medicine (Division of Cardiology), Baylor College of Medicine, Houston, TX 77030

    X.H.T. WEHRENS

Authors
  1. W.J. DURHAM
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  2. X.H.T. WEHRENS
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  3. S. SOOD
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  4. S.L. HAMILTON
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Editor information

Editors and Affiliations

  1. University of Padova, Padova, Italy

    Ernesto Carafoli

  2. University of Padova, Padova, Italy

    Marisa Brini

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© 2007 Springer

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DURHAM, W., WEHRENS, X., SOOD, S., HAMILTON, S. (2007). Diseases associated with altered ryanodine receptor activity. In: Carafoli, E., Brini, M. (eds) Calcium Signalling and Disease. Subcellular Biochemistry, vol 45. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6191-2_10

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