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Calcium Signalling and Disease

Molecular pathology of calcium

  • Book
  • © 2007

Overview

Editors:
  1. Ernesto Carafoli

    1. University of Padova, Padova, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Marisa Brini

    1. University of Padova, Padova, Italy

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    You can also search for this editor in PubMed   Google Scholar

  • First book of this type
  • New, powerfully emerging topic
  • Interdisciplinary book, from biochemistry to clinics

Part of the book series: Subcellular Biochemistry (SCBI, volume 45)

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Table of contents (21 chapters)

  1. Front Matter

    Pages I-XII
    Download chapter PDF

  2. Annexinopathies

    • M.J. HAYES, R.E. LONGBOTTOM, M.A. EVANS, S.E. MOSS
    Pages 1-28

  3. Calpains and Human Disease

    • I. BERTIPAGLIA, E. CARAFOLI
    Pages 29-53

  4. Gelsolin and Diseases

    • L. SPINARDI, W. WITKE
    Pages 55-69

  5. Guanylate Cyclase-Activating Proteins and Retina Disease

    • W. BAEHR, K. PALCZEWSKI
    Pages 71-91

  6. Pathologies Involving the S100 Proteins and Rage

    • C.W. HEIZMANN, G.E. ACKERMANN, A. GALICHET
    Pages 93-138

  7. The Calcium-Sensing Receptor: Physiology, Pathophysiology and Car-Based Therapeutics

    • E.M. BROWN
    Pages 139-167

  8. Physiological Roles Of The Ca2+/Cam-Dependent Protein kinase Cascade In Health and Disease

    • J. COLOMER, A.R. MEANS
    Pages 169-214

  9. Calcium Channelopathies: Voltage-Gated Calcium Channels

    • P.J. ADAMS, T.P. SNUTCH
    Pages 215-251

  10. Trp Channels In Disease

    • S.E. JORDT, B.E. EHRLICH
    Pages 253-271

  11. Diseases associated with altered ryanodine receptor activity

    • W.J. DURHAM, X.H.T. WEHRENS, S. SOOD, S.L. HAMILTON
    Pages 273-321

  12. Inositol 1,4,5-tripshosphate receptor, calcium signalling and huntington’s disease

    • I. Bezprozvanny
    Pages 323-335

  13. Serca pumps and human diseases

    • A. HOVNANIAN
    Pages 337-363

  14. The plasma membrane calcium ATPase and disease

    • B.L Tempel, D.J. Shilling
    Pages 365-383

  15. Diseases involving the Golgi calcium pump

    • J. VANOEVELEN, L. DODE, L. RAEYMAEKERS, F. Wuytack, L. Missiaen
    Pages 385-404

  16. Calcium signalling and cancer cell growth

    • T. CAPIOD, Y. SHUBA, R. SKRYMA, N. PREVARSKAYA
    Pages 405-427

  17. Calcium Misregulation and the Pathogenesis of Muscular Dystrophy

    • F.W. HOPF, P.R. TURNER, R.A. STEINHARDT
    Pages 429-464

  18. Calcium and Cell Death

    • A. VERKHRATSKY
    Pages 465-480

  19. Calcium and Cell Death: The Mitochondrial Connection

    • P. BERNARDI, A. RASOLA
    Pages 481-506

  20. Role of Calcium in the Pathogenesis of Alzheimer’s Disease and Transgenic Models

    • K.N. GREEN, I.F. SMITH, F.M. LAFERLA
    Pages 507-521
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Keywords

About this book

This topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy.

Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer’s disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).

Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.

Editors and Affiliations

  • University of Padova, Padova, Italy

    Ernesto Carafoli, Marisa Brini

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