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Surfactants

  • Chapter
Physicochemical Principles of Pharmacy

Abstract

Certain compounds, because of their chemical structure, have a tendency to accumulate at the boundary between two phases. Such compounds are termed amphiphiles, surfaceactive agents or surfactants. The adsorption at the various interfaces between solids, liquids and gases results in changes in the nature of the interface which are of considerable importance in pharmacy. For example, the lowering of the interfacial tension between oil and water phases facilitates emulsion formation, the adsorption of surfactants on insoluble particles enables these particles to be dispersed in the form of a suspension, and the incorporation of insoluble compounds within micelles of the surfactant can lead to the production of clear solutions.

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Author information

Authors and Affiliations

  1. The School of Pharmacy, University of London, UK

    A. T. Florence

  2. School of Pharmacy and Pharmaceutical Sciences, University of Manchester, UK

    D. Attwood

Authors
  1. A. T. Florence
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  2. D. Attwood
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© 1998 A. T. Florence and D. Attwood

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Florence, A.T., Attwood, D. (1998). Surfactants. In: Physicochemical Principles of Pharmacy. Palgrave, London. https://doi.org/10.1007/978-1-349-14416-7_7

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  • DOI: https://doi.org/10.1007/978-1-349-14416-7_7

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-0-333-69081-9

  • Online ISBN: 978-1-349-14416-7

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