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  • Textbook
  • © 1998

Physicochemical Principles of Pharmacy

  • Uses real drugs and excipients as examples in order to teach the principles of pharmaceutical formulation and pharmaceutical systems
    Provides the underlying scientific knowledge required for the practice of pharmarcy
    Text has been rewritten and reorganised, retaining the emphasis on physical chemistry in order to describe formulations and how they work
    New chapters on proteins and peptides and on macromolecular drugs
    Many new illustrations are included

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xi
  2. Introduction

    • A. T. Florence, D. Attwood
    Pages 1-4
  3. Properties of the Solid State

    • A. T. Florence, D. Attwood
    Pages 5-35
  4. Gases and Volatile Agents

    • A. T. Florence, D. Attwood
    Pages 36-55
  5. Physicochemical Properties of Drugs in Solution

    • A. T. Florence, D. Attwood
    Pages 56-100
  6. Drug Stability

    • A. T. Florence, D. Attwood
    Pages 101-151
  7. The Solubility of Drugs

    • A. T. Florence, D. Attwood
    Pages 152-198
  8. Surfactants

    • A. T. Florence, D. Attwood
    Pages 199-251
  9. Emulsions, Suspensions and Other Dispersions

    • A. T. Florence, D. Attwood
    Pages 252-307
  10. Polymers and Macromolecules

    • A. T. Florence, D. Attwood
    Pages 308-371
  11. Drug Absorption and Routes of Administration

    • A. T. Florence, D. Attwood
    Pages 372-448
  12. Physicochemical Drug Interactions and Incompatibilities

    • A. T. Florence, D. Attwood
    Pages 449-492
  13. Peptides and Proteins

    • A. T. Florence, D. Attwood
    Pages 493-526
  14. Assessment of Dosage Forms In Vitro

    • A. T. Florence, D. Attwood
    Pages 527-550
  15. Back Matter

    Pages 551-564

About this book

Florence and Attwood's well known textbook uses pharmaceutical examples to illustrate the underlying physical chemistry of drug characterisation, formulation, delivery, transport and adsorption. Students of pharmacology, toxicology, medicine and researchers will want this book.

Authors and Affiliations

  • The School of Pharmacy, University of London, UK

    A. T. Florence

  • School of Pharmacy and Pharmaceutical Sciences, University of Manchester, UK

    D. Attwood

About the authors

ALEXANDER FLORENCE is Dean of the School of Pharmacy and Professor of Pharmacy in the University of London. He was previously Professor of Pharmaceutics at the University of Strathclyde. His research interests are in the relationship between the physical characteristics of formulations and their biological effect, with an emphasis on the surface and colloid chemical character of pharmaceutical systems.

DAVID ATTWOOD is Reader in Pharmacy at the University of Manchester; he previously lectured at the University of Strathclyde. He has numerous publications on the physicochemical properties of drugs and surfactants and in the area of controlled drug delivery and has many years' experience in the teaching of physical pharmacy.

Bibliographic Information