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Immunotoxicology and Allergy: Options for Ex Vivo and In Vitro Experimentation

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Animals and Alternatives in Toxicology

Abstract

The purpose of this review is to identify the potential benefits and limitations of in vitro and ex vivo techniques in the identification of immunotoxicants and allergens, and in the investigation of the mechanisms through which chemicals perturb immune function.

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Authors and Affiliations

  1. ICI Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, UK

    Philip A. Botham & Ian Kimber

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  1. Philip A. Botham
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  2. Ian Kimber
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Editor information

Editors and Affiliations

  1. University of Nottingham, UK

    Michael Balls (Professor of Medical Cell Biology) (Professor of Medical Cell Biology)

  2. University of Surrey, Guildford, UK

    James Bridges (Professor of Toxicology) (Professor of Toxicology)

  3. FRAME, Nottingham, UK

    Jacqueline Southee (Scientific Executive) (Scientific Executive)

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© 1991 FRAME

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Botham, P.A., Kimber, I. (1991). Immunotoxicology and Allergy: Options for Ex Vivo and In Vitro Experimentation. In: Balls, M., Bridges, J., Southee, J. (eds) Animals and Alternatives in Toxicology. Palgrave, London. https://doi.org/10.1007/978-1-349-12667-5_6

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  • DOI: https://doi.org/10.1007/978-1-349-12667-5_6

  • Publisher Name: Palgrave, London

  • Print ISBN: 978-1-349-12669-9

  • Online ISBN: 978-1-349-12667-5

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