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Abstract

It is now a decade since the prototype CD7 monoclonal antibody (Mab) 3A1 was described (Haynes, Eisenbarth, and Fauci, 1979). At this time ten years ago it was first noted that 3A1+ cells respond more vigorously upon stimulation with lectins than 3A1 ones, suggesting that this Mab identifies a large functionally distinct set of T cells. Mab 3A1 and two other Mabs, 4A and CL1-3, were designated as the CD7 cluster at the First Leucocyte Typing Workshop. Since then many CD7 Mabs have been produced, some of which are listed in Table 18.1.

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Carl A. K. Borrebaeck James W. Larrick

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© 1990 Stockton Press

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Amlot, P., Cammisuli, S. (1990). CD7 Monoclonal Antibodies. In: Borrebaeck, C.A.K., Larrick, J.W. (eds) Therapeutic Monoclonal Antibodies. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-11894-6_18

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