CD7 Monoclonal Antibodies

  • Peter Amlot
  • Salvatore Cammisuli


It is now a decade since the prototype CD7 monoclonal antibody (Mab) 3A1 was described (Haynes, Eisenbarth, and Fauci, 1979). At this time ten years ago it was first noted that 3A1+ cells respond more vigorously upon stimulation with lectins than 3A1 ones, suggesting that this Mab identifies a large functionally distinct set of T cells. Mab 3A1 and two other Mabs, 4A and CL1-3, were designated as the CD7 cluster at the First Leucocyte Typing Workshop. Since then many CD7 Mabs have been produced, some of which are listed in Table 18.1.


Acute Myeloid Leukemia Rejection Episode Multipotent Stem Cell Severe Combine Immunodeficiency Disease Therapeutic Monoclonal Antibody 
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Copyright information

© Stockton Press 1990

Authors and Affiliations

  • Peter Amlot
  • Salvatore Cammisuli

There are no affiliations available

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