New Therapeutic Approaches in Recurrent Metastatic Disease

Abstract

One of the major obstacles limiting successful cancer therapy is the ability of malignant cells to overcome the immune defense system and form resistant foci of metastatic tumor cells in different locations. Until very recently the appearance of metastases meant a high probability of death. Although there is no single clinically useful agent that could be defined as a specific antimetastatic drug, advances have been made in the treatment of some metastatic cancers during the last decade.