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New Concepts in Cancer

Metastasis, Oncogenes and Growth Factors

  • C. Etievant
  • J. Cros
  • Y. M. Rustum
Textbook

Table of contents

  1. Front Matter
    Pages i-ix
    PDF
  2. New Therapeutic Approaches in Recurrent Metastatic Disease
    M. Boiron
    Pages 1-7
  3. Features of Tumor Progression in H-ras transformed Rat Embryo Cells
    Ruth J. Muschel, Martha Sack, Marisa C. Weiss, Vincent J. Bakanauskas, W. Gillies McKenna
    Pages 8-21
  4. Organ Specificity of Metastasis: Adhesive, Invasive and Growth Properties of Organ-Specific Metastatic Cells
    Garth L. Nicolson
    Pages 22-41
  5. Role of 12-Lipoxygenase Metabolites and Integrin Glycoprotein Receptors in Metastasis
    Kenneth V. Honn, Irma M. Grossi, Clement A. Diglio, John D. Taylor
    Pages 42-62
  6. The Rapid Destruction of Cancer Cells in the Microvasculature
    Leonard Weiss
    Pages 63-73
  7. The Control of Cell Movement by Laminin, and its Role in Metastasis
    J. C. Lissitzky, M. Bouzon, P. Delori, C. Bignon, P. Cantau, P. M. Martin
    Pages 74-92
  8. Dormant Metastatic Cells: Hypotheses on Mechanisms, Magnitude, Failure and Control
    Lucien Israel
    Pages 93-99
  9. Estrogen-induced Pro-cathepsin D and its Relationship to Breast Cancer Invasion and Metastasis
    Henri Rochefort, Patrick Augereau, Pierre Briozzo, Jean-Paul Brouillet, Françoise Capony, Vincent Cavaillès et al.
    Pages 100-110
  10. Metastatic Process Does Not Select Cells for Metastatic Ability But Metastatic Cells Are Selected for by Drug Resistance. Implications for Tumor Progression
    Marie-France Poupon, Nicole Hanania, Maria-Dolores Boyano, Etienne Antoine, Yvette Rolland, Fabienne Breillout et al.
    Pages 111-126
  11. Calcium Channel Blockers and Cisplatin: Synergistic Antimetastatic Effects
    James M. Onoda, Marie P. Piechocki, Roxana G. Mihu, Kevin K. Nelson
    Pages 127-147
  12. Assays In Vitro and In Vivo for Invasion and Metastasis: Application to Drug Testing
    M. Mareel, M. Bracke, E. Bruyneel, N. Van Larebeke, L. Bourgois, M. De Mets
    Pages 148-165
  13. The Structure and Function of Growth Factor Receptors and Their Subversion in Cancer
    G. Panayotou, J. D. Haley, J. J. Hsuan, S. Clark, M. D. Waterfield
    Pages 166-180
  14. Cell Growth Signaling in Fibroblasts: the Role of G-Proteins
    J. Pouysségur, C. Kahan, I. Magnaldo, K. Seuwen
    Pages 181-195
  15. The Bombesin Receptor Complex and Cell Growth: Physiology and Pathology
    G. Gaudino, L. Gandino, M. Cilli, A. Mondino, P. M. Comoglio
    Pages 196-207
  16. Hormonal Effects on Gastrointestinal Cancer Growth
    Courtney M. Townsend Jr, Pomila Singh, James C. Thompson
    Pages 208-217
  17. Regulation of Fibroblastic and Epithelial Cell Function by Transforming Growth Factors
    H. L. Moses, J. A. Barnard, C. C. Bascom, R. D. Beauchamp, R. M. Lyons, D. A. Miller et al.
    Pages 218-230
  18. Back Matter
    Pages 231-236
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About this book

Introduction

This book defines and reviews the clinical status of metastatic disease and the present status of response to radiation and chemotherapy, identifies factors associated with and/or responsible for tumor metastasis and evaluates the role of various growth factors in metastasis and therapy. It also considers the possible relationship between the overexpression of oncogenes and clinical resistance to chemotherapy and possible therapeutic strategies arising from this relationship, if proven.

Keywords

breast cancer cancer cell chemotherapy metastasis metastatic disease pathology tumor tumor progression

Editors and affiliations

  • C. Etievant
    • 1
  • J. Cros
    • 2
  • Y. M. Rustum
    • 3
  1. 1.Pierre Fabre MédicamentCastresFrance
  2. 2.CNRSToulouseFrance
  3. 3.Roswell Park Memorial HospitalBuffaloUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-349-10671-4
  • Copyright Information Macmillan Publishers Limited 1990
  • Publisher Name Palgrave, London
  • eBook Packages Engineering
  • Print ISBN 978-1-349-10673-8
  • Online ISBN 978-1-349-10671-4
  • Buy this book on publisher's site
Industry Sectors
Pharma
Health & Hospitals
Biotechnology