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Imaging of Angiogenesis

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Angiogenesis

The imaging of angiogenesis has advanced from a scientific curiosity to an important tool in the assessment of new drugs. Virtually every imaging modality has a potential role to play in this arena. The best understood and widely available are dynamic contrast enhanced magnetic resonance imaging (MRI) and computed tomography (CT), but these modalities are by no means the only methods. Here, we discuss other MRI techniques, as well as ultrasound, optical and positron emission tomography (PET), as potential tools in assessing angiogenesis. We also consider the future role of molecular imaging methods that rely on targeting probes of biomarkers of angiogenesis. Finally, we review the considerations in implementing imaging methods into clinical trials of angiogenic inhibitors.

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Authors and Affiliations

  1. Center for Cancer Research, National Cancer Institute, 20892, Bethesda, MD, USA

    Tristan Barrett & Peter L. Choyke

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  1. Tristan Barrett
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  2. Peter L. Choyke
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Editors and Affiliations

  1. Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA

    William D. Figg

  2. Department of Surgery Harvard Medical School and Vascular Biology Program, Children's Hospital Boston, Boston, MA, USA

    Judah Folkman

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Barrett, T., Choyke, P.L. (2008). Imaging of Angiogenesis. In: Figg, W.D., Folkman, J. (eds) Angiogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-71518-6_28

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  • DOI: https://doi.org/10.1007/978-0-387-71518-6_28

  • Publisher Name: Springer, Boston, MA

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