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The Threonine Story

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Microbial Production of l-Amino Acids

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 79))

Abstract

l-Threonine is an essential amino acid which has recently been brought into agricultural industry for balancing the livestock feed. l-Threonine is produced by microbial synthesis using glucose or sucrose as substrates. For the process to be cost-effective, the microbial strain must be capable of threonine overproduction. This paper reviews the biochemical pathways of l-threonine synthesis in bacteria and the regulation of these pathways, the principles and the techniques of constructing high-producing strains, and the most efficient strains thus developed.

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  1. State Research Institute of Genetics and Selection of Industrial Microorganisms, 1st Dorozhnyi proezd, Moscow, 113545, Russia

    Vladimir G. Debabov

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  1. Vladimir G. Debabov
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  1. AMINO GmbH, An der Zucker-Raffinerie 10, 38373, Frellstedt, Germany

    Robert Faurie  & Jügen Thommel  & 

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Debabov, V.G. (2003). The Threonine Story. In: Faurie, R., et al. Microbial Production of l-Amino Acids. Advances in Biochemical Engineering/Biotechnology, vol 79. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45989-8_4

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  • DOI: https://doi.org/10.1007/3-540-45989-8_4

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