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Interaction Between Cytochrome c and Oxidized Mitochondrial Lipids

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Phospholipid Metabolism in Apoptosis

Part of the book series: Subcellular Biochemistry ((SCBI,volume 36))

Conclusions

In this chapter, we have postulated that cardiolipin may participate in determination of cell fate by allowing cytochrome c release from mitochondrial inner membrane through its peroxidative damage during apoptotic cell death. And anti-oxidant mitochondrial enzyme, PHGPx may protect cardiolipin from its peroxidation as well as apoptotic cell death.

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Author information

Authors and Affiliations

  1. Cellular Biochemistry Section, Department of Nutrition and Health Sciences, Siebold University of Nagasaki, Nagayo, Japan

    Yoshihiro Shidoji

  2. Institute of Applied Biochemistry, Yagi Memorial Park, Mitake, Giu, Japan

    Sadaaki Komura, Nobuko Ohishi & Kunio Yagi

Authors
  1. Yoshihiro Shidoji
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  2. Sadaaki Komura
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  3. Nobuko Ohishi
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  4. Kunio Yagi
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Editor information

Editors and Affiliations

  1. Kings College London, London, UK

    Peter J. Quinn

  2. University of Pittsburgh, Pittsburgh, Pennsylvania

    Valerian E. Kagan

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© 2004 Kluwer Academic Publishers

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Shidoji, Y., Komura, S., Ohishi, N., Yagi, K. (2004). Interaction Between Cytochrome c and Oxidized Mitochondrial Lipids. In: Quinn, P.J., Kagan, V.E. (eds) Phospholipid Metabolism in Apoptosis. Subcellular Biochemistry, vol 36. Springer, Boston, MA. https://doi.org/10.1007/0-306-47931-1_2

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  • DOI: https://doi.org/10.1007/0-306-47931-1_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46782-0

  • Online ISBN: 978-0-306-47931-1

  • eBook Packages: Springer Book Archive

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