Skip to main content

Intrahepatic Expression of Collagen and Fibroblast Activation Protein (FAP) in Hepatitis C Virus Infection

  • Chapter
Dipeptidyl Aminopeptidases in Health and Disease

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Gorrell, M. D., Gysbers, V. and McCaughan, G. W., 2001, CD26: A multifunctional integral membrane and secreted protein of activated lymphocytes. Scand. J. Immunol. 54: 249–64.

    Article  PubMed  CAS  Google Scholar 

  2. Abbott, C. A. and Gorrell, M. D., 2002, The family of CD26/DPIV and related ectopeptidases. In Ectopeptidases: CD13/Aminopeptidase N and CD26/Dipeptidylpeptidase IV in Medicine and Biology (J. Langner and S. Ansorge ed.), Vol. ISBN 0-306-46788-7 Kluwer/Plenum, NY, p. 171–95.

    Google Scholar 

  3. Abbott, C. A., McCaughan, G. W. and Gorrell, M. D., 1999, Two highly conserved glutamic acid residues in the predicted beta propeller domain of dipeptidyl peptidase IV are required for its enzyme activity. FEBS Lett. 458: 278–84.

    Article  PubMed  CAS  Google Scholar 

  4. McCaughan, G. W., Gorrell, M. D., Bishop, G. A., Abbott, C. A., Shackel, N. A., McGuinness, P. H., Levy, M. T., Sharland, A. F., Bowen, D. G., Yu, D., Slaitini, L., Church, W. B. and Napoli, J., 2000, Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance. Immunol. Rev. 174: 172.

    Article  PubMed  CAS  Google Scholar 

  5. Levy, M. T., McCaughan, G. W., Abbott, C. A., Park, J. E., Cunningham, A. M., Rettig, W. J. and Gorrell, M. D., 1999, Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis. Hepatology 29: 1768–78.

    Article  PubMed  CAS  Google Scholar 

  6. Park, J. E., Lenter, M. C., Zimmermann, R. N., Garin-Chesa, P., Old, L. J. and Rettig, W. J., 1999, Fibroblast activation protein: A dual-specificity serine protease expressed in reactive human tumor stromal fibroblasts. J. Biol. Chem. 274: 36505–12.

    PubMed  CAS  Google Scholar 

  7. Rettig, W. J., Su, S. L., Fortunato, S. R., Scanlan, M. J., Raj, B. K., Garin-Chesa, P., Healey, J. H. and Old, L. J., 1994, Fibroblast activation protein: purification, epitope mapping and induction by growth factors. Int. J. Cancer 58: 385–92.

    PubMed  CAS  Google Scholar 

  8. Benyon, R. C. and Arthur, M. J. P., 2001, Extracellular matrix degradation and the role of hepatic stellate cells. Sem. Liver Dis. 21: 373–84.

    CAS  Google Scholar 

  9. Schmitt-Graff, A., Kruger, S., Bochard, F., Gabbiani, G. and Denk, H., 1991, Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am. J. Pathol. 138: 1233–42

    PubMed  CAS  Google Scholar 

  10. Gauderon, R., Lukins, P. B. and Sheppard, C. J., 2001, Optimization of second-harmonic generation microscopy. Micron 32: 691–700.

    PubMed  CAS  Google Scholar 

  11. Cox, G., Kable, E., Jones, A., Fraser, I., Manconi, F. and Gorrell, M. D., 2002, Three-dimensional imaging of collagen using second harmonic generation. J. Struct. Biol.

    Google Scholar 

  12. Herrera, C., Morimoto, C., Blanco, J., Mallol, J., Arenzana, F., Lluis, C. and Franco, R., 2001, Comodulation of CXCR4 and CD26 in human lymphocytes. J. Biol. Chem. 276: 19532–9.

    Article  PubMed  CAS  Google Scholar 

  13. Goddard, C. J., Smith, A., Hoyland, J. A., Baird, P., McMahon, R. F., Freemont, A. J., Shomaf, M., Haboubi, N. Y. and Warnes, T. W., 1998, Localisation and semiquantitative assessment of hepatic procollagen mRNA in primary biliary cirrhosis. Gut 43: 433–40.

    PubMed  CAS  Google Scholar 

  14. Cassiman, D., Libbrecht, L., Desmet, V., Denef, C. and Roskams, T., 2002, Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers. J. Hepatol. 36: 200–9.

    PubMed  Google Scholar 

  15. Maher, J. J., 2001, Interactions between hepatic stellate cells and the immune system. Sem. Liver Dis. 21: 417–26.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2004 Kluwer Academic Publishers

About this chapter

Cite this chapter

Gorrell, M.D. et al. (2004). Intrahepatic Expression of Collagen and Fibroblast Activation Protein (FAP) in Hepatitis C Virus Infection. In: Back, N., Cohen, I.R., Kritchevsky, D., Lajtha, A., Paoletti, R. (eds) Dipeptidyl Aminopeptidases in Health and Disease. Advances in Experimental Medicine and Biology, vol 524. Springer, Boston, MA. https://doi.org/10.1007/0-306-47920-6_28

Download citation

  • DOI: https://doi.org/10.1007/0-306-47920-6_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-47717-1

  • Online ISBN: 978-0-306-47920-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics