Abstract
Every year, open globe injuries (OGIs) affect approximately 266,000 patients worldwide (Negrel and Thylefors B. Ophthalmic Epidemiol. 1998;5:143–69). The management of these patients remains controversial, particularly for the following areas: antibiotic prophylaxis for endophthalmitis, repair of posterior ruptures, injuries with lens disruption, repair of eyes with no light perception (NLP), and the risk for developing sympathetic ophthalmia. This chapter will review these controversial topics in the management of open globe injuries. We will first present an evidence based review of the current literature in this area, followed by an expert opinion by one of our editors.
Expert Opinions by: Christopher Andreoli, M.D., Michael Yoon, M.D., Lucia Sobrin, M.D., M.P.H., Alice Lorch M.D., Peter Veldman, M.D., Dean Eliott M.D.
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References
Negrel AD, Thylefors B. The global impact of eye injuries. Ophthalmic Epidemiol. 1998;5:143–69.
Narang S, Gupta V, Gupta A, et al. Role of prophylactic intravitreal antibiotics in open globe injuries. Indian J Ophthalmol. 2003;51:39–44.
Lorch A, Sobrin L. Prophylactic antibiotics in posttraumatic infectious endophthalmitis. Int Ophthalmol Clin. 2013;53:167–76.
Mieler WF, Ellis MK, Williams DF, et al. Retained intraocular foreign bodies and endophthalmitis. Ophthalmology. 1990;97:1532.
Banker TP, McClellan AJ, Wilson BD, et al. Culture-positive endophthalmitis after open globe injuries with and without retained intraocular foreign bodies. Ophthalmic Surg Lasers Imaging Retina. 2016;48(8):632–7.
Chhabra S, Kunimoto DY, Kazi L, et al. Endophthalmitis after open globe injury: microbiologic spectrum and susceptibilities of isolates. Am J Ophthalmol. 2006;142:852–4.
Bhagat N, Nagori S, Zarbin M. Post-traumatic Infectious Endophthalmitis. Surv Ophthalmol. 2001;56:214–51.
Soheilian M, Rafati N, Mohebbi MR, et al. Prophylaxis of acute posttraumatic bacterial endophthalmitis: a multicenter, randomized clinical trial of intraocular antibiotic injection, report 2. Arch Ophthalmol. 2007;125(4):460–5.
Andreoli CM, Andreoli MT, Kloek CE, et al. Low rate of endophthalmitis in a large series of open globe injuries. Am J Ophthalmol. 2009;147(4):601–8.
Tabatabaei SA, Soleimani M, Behrooz MJ, et al. Systemic oral antibiotics as a prophylactic measure to prevent endopthalmitis in patients with open globe injuries in comparison with intravenous antibiotics. Retina. 2016;36:360–5.
Du toit N, Mustak S, Cook C. Randomized controlled trial of prophylactic antibiotic treatment for the prevention of endophthalmitis after open globe injury at Groote Schuur Hospital. Br J Ophthalmol. 2017;101:862–7.
Saeed MU, Chang BY, Khandwala M, et al. Twenty year review of histopathological findings in enucleated/eviscerated eyes. J Clin Pathol. 2006;59(2):153–5.
Moshfeghi DM, Moshfeghi AA, Finger PT. Enucleation. Surv Ophthalmol. 2000;44:277–301.
Salehi-Had H, Andreoli CM, Andreoli MT, et al. Visual outcomes of vitreoretinal surgery in eyes with severe open-globe injury presenting with no-light-perception vision. Graefes Arch Clin Exp Ophthalmol. 2009;247:477–83.
Han YS, Kavoussi SC, Adelman RA. Visual recovery following open globe injury with initial no light perception. Clin Ophthalmol. 2015;9:1443–8.
Bhagat N, Turbin R, Langer P, et al. Approach to management of eyes with no light perception after open globe injury. J Ophthalmic Vis Res. 2016;11(3):313–8.
Savar A, Andreoli MT, Kloek CE, et al. Enucleation for open globe injury. Am J Ophthalmol. 2009;147:595–600.
McAlinden C, Saldanha M, Laws D. Evisceration for the management of ocular trauma. BMJ Case Rep. https://doi.org/10.1136/bcr-2013-201235.
Zheng C, Wu AY. Enucleation versus evisceration in ocular trauma: a retrospective review and study of current literature. Orbit. 2013;32(6):356–61.
du Toit N, Motala MI, Richards J, et al. The risk of sympathetic ophthalmia following evisceration for penetrating eye injuries at Groote Schuur Hospital. Br J Ophthalmol. 2008;92:61–3.
O’Donnell BA, Kersten R, McNab A, et al. Enucleation versus evisceration. Clin Experiment Ophthalmol. 2005;33(1):5–9.
Nakra T, Simon GJ, Douglas RS, et al. Comparing outcomes of enucleation and evisceration. Ophthalmology. 2006;113(12):2270–5.
Tari AS, Malihi M, Kasaee A, et al. Enucleation with hydroxyapatite implantation versus evisceration plus scleral quadrisection and alloplastic implantation. Ophthal Plast Reconstr Surg. 2009;25(2):130–3.
Ababneh OH, AboTaleb EA, Abu Ameerh MA, et al. Enucleation and evisceration at a tertiary care hospital in a developing country. BMC Ophthalmol. 2015;15:120.
Frost WA. What is the best method of dealing with a lost eye? Br Med J. 1887;1(1378):1153–4.
Ruedemann AD Jr. Sympathetic ophthalmia after evisceration. Am J Ophthalmol. 1964;57:770–90.
Green WR, Maumenee AE, Sanders TE, et al. Sympathetic uveitis following evisceration. Trans Am Acad Ophthalmol Otolaryngol. 1972;76(3):625–44.
Friedlin J, Pak J, Tessler HH, et al. Sympathetic ophthalmia after injury in the Iraq War. Ophthal Plast Reconstr Surg. 2006;22(2):133–4.
Pieramici DJ, MacCumber MW, Humayun MU, et al. Open-globe injury. Update on types of injuries and visual results. Ophthalmology. 1996;103(11):1798–803.
Soni NG, Bauza AM, Son JH, et al. Open globe ocular trauma: functional outcome of eyes with no light perception at initial presentation. Retina. 2013;33(2):380–6.
Schmidt GW, Broman AT, Hindman HB. Vision survival after open globe injury predicted by classification and regression tree analysis. Ophthalmology. 2008;115(1):202–9.
Feng K, Hu YT, Ma Z. Prognostic indicators for no light perception after open-globe injury: eye injury vitrectomy study. Am J Ophthalmol. 2011;152(4):654–662.e2.
Agrawal R, Wei HS, Teoh S. Predictive factors for final outcome of severely traumatized eyes with no light perception. BMC Ophthalmol. 2012;12:16.
Chee YE, Kanoff JM, Eliott D. Remarkable visual recovery after severe open globe injury. Am J Ophthalmol Case Rep. 2016;3:34–5.
Kuhn F, Maisiak R, Mann L, et al. The Ocular Trauma Score (OTS). Ophthalmol Clin North Am. 2002;15(2):163–5.
Ye J, Lou L, Jin K, et al. Vision-related quality of life and appearance concerns are associated with anxiety and depression after eye enucleation: a cross-sectional study. PLoS One. 2015;10(8):e0136460.
Hope-Stone L, Brown SL, Heimann H, et al. Phantom eye syndrome: patient experiences after enucleation for uveal melanoma. Ophthalmology. 2015;122(8):1585–90.
Lubin JR, Albert DM, Weinstein M. Sixty-five years of sympathetic ophthalmia: a clinicopathologic review of 105 cases. Ophthalmology. 1980;87(2):109–21.
Cunningham ET, Kilmartin D, Agarwal M, Zierhut M. Sympathetic ophthalmia. Ocular Immun Inflamm. 2017;25(2):149–51.
Castiblanco CP, Adelman RA. Sympathetic ophthalmia. Graefes Arch Clin Exp Ophthalmol. 2009;247:289–302.
Aziz HA, Flynn HW, Young RC. Sympathetic ophthalmia: clinicopathologic correlation in a consecutive case series. Retina. 2015;35(8):1696–703.
Dor L. La guérison des deux yeux dans l'ophtalmie sympathique. Arch d'Opht. 1931;48:811.
Fuchs A. Arch Oftal B. Aires. 1932;7:67.
Joy HH. A survey of cases of sympathetic ophthalmia occurring in New York State. Arch Ophthalmol. 1935;14(5):733–41.
Irvine R. Sympathetic ophthalmia: a clinical review of 63 cases. Arch Ophthalmol. 1940;24:149–67.
Stafford WR. Sympathetic ophthalmia. Report of a case occurring ten and one-half days after injury. Arch Ophthamol. 1965;74:521–4.
Nettleship E. Trans Ophthal Soc UK. 1886;170.
Muga R, Maul E. The management of lens damage in perforating corneal lacerations. Br J Ophthalmol. 1978;62(11):784–7.
Assi A, Chacra CB, Cherfan G. Combined lensectomy, vitrectomy, and primary intraocular lens implantation in patients with traumatic eye injury. Int Ophthalmol. 2008;28(6):387–94.
Rubsamen PE, Irvin WD, McCuen BW, et al. Primary intraocular lens implantation in the setting of penetrating ocular trauma. Ophthalmology. 1995;102(1):101–7.
Hikichi T, Yoshida A, Hasegawa T, Ohnishi M, Sato T, Muraoka S. Wound healing of scleral self-sealing incision: a comparison of ultrasound biomicroscopy and histology findings. Graefes Arch Clin Exp Ophthalmol. 1998;236(10):775–8.
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Tieger, M.G., Kloek, C., Lorch, A.C. (2018). Controversies in Open Globe Injury Management. In: Grob, S., Kloek, C. (eds) Management of Open Globe Injuries. Springer, Cham. https://doi.org/10.1007/978-3-319-72410-2_5
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DOI: https://doi.org/10.1007/978-3-319-72410-2_5
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