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Fcγ Receptors of Myeloid Cells

  • Chapter
Macrophages and Related Cells

Part of the book series: Blood Cell Biochemistry ((BLBI,volume 5))

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Abstract

Fc receptors (FcRs) are cell surface molecules that mediate interactions between cells and immunoglobulins. Phagocytic cells, such as monocytes/macrophages, neutrophils, and eosinophils, need FcRs for the binding, ingestion, and destruction of particles opsonized by antibodies. The FcRs bind the Fc regions of immunoglobulins, thus establishing contact between the cell that carries FcRs on its surface and the antigen bound to the Fab region of the immunoglobulin.

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de Haas, M., Huizinga, T.W.J., van de Winkel, J.G.J., Roos, D., von dem Borne, A.E.G.K. (1993). Fcγ Receptors of Myeloid Cells. In: Horton, M.A. (eds) Macrophages and Related Cells. Blood Cell Biochemistry, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9534-9_10

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