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Women’s Health and Menopause

Risk Reduction Strategies

  • Book
  • © 1997

Overview

Editors:
  1. R. Paoletti

    1. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

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  2. P. G. Crosignani

    1. Department of Obstetrics and Gynecology, University of Milan, Milan, Italy

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  3. P. Kenemans

    1. Department of Obstetrics and Gynaecology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands

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  4. G. Samsioe

    1. Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden

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  5. M. R. Soma

    1. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

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  6. A. S. Jackson

    1. Giovanni Lorenzini Medical Foundation, Houston, USA

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Part of the book series: Medical Science Symposia Series (MSSS, volume 11)

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Table of contents (47 chapters)

  1. Front Matter

    Pages i-xxix
    Download chapter PDF

  2. Menopause as a Medical and Social Issue

    1. The Problem of Menopause in Europe

      • Martin H. Birkhäuser
      Pages 1-7

    2. Menopause: Problems and Interventions in the United States

      • Elizabeth Barrett-Connor
      Pages 9-13

    3. Hormone Replacement Therapy and Oral Contraceptives: Limitations of Epidemiological Studies

      • Martin P. Vessey
      Pages 15-23

  3. Ovarian Senescence

    1. Genetic Factors in Follicular Aging

      • C. H. Matthews
      Pages 25-27

    2. Premature Menopause

      • Martin H. Birkhäuser
      Pages 29-38

    3. When Should Hormonal Replacement Therapy Be Introduced? Associated Problems

      • Antti Kauppila
      Pages 39-44

  4. Connective Tissue and Bone

    1. Connective Tissue Changes

      • Mark Brincat, Ray Galea
      Pages 45-53

    2. The Effect of Low Dose Estrogen on Bone Mass in the Late Postmenopausal Years

      • M. Meschia, F. Bruschi, F. Amicarelli, P. Pifarotti, M. Rossi, P. G. Crosignani
      Pages 55-59

    3. Perimenopausal Changes in Body Weight, Body Fat Distribution and Hormonal Replacement Therapy

      • Marco Gambacciani, Massimo Ciaponi, Barbara Cappagli, Laura Piaggesi, Caterina Benussi, Stefania Picchetti et al.
      Pages 61-67

  5. Osteoporosis

    1. The Effects of Estrogen Receptor Gene Disruption on Bone

      • Kenneth S. Korach, Motohiko Taki, K. Sean Kimbro
      Pages 69-73

    2. Osteoporosis: Different Treatment Options

      • Claus Christiansen
      Pages 75-78

    3. Inherited Risk of Osteoporosis: A Piece in the Puzzle of Menopause Genetics

      • Maria Luisa Brandi
      Pages 79-85

    4. Estrogen Replacement Therapy and Osteoporosis: Practical Implications of New Research Findings

      • Elizabeth Barrett-Connor
      Pages 87-90

  6. Cardiovascular Risk

    1. HRT, Plasma Risk Factors, and Cardiovascular Disease

      • Gerd Assmann, Paul Cullen, Helmut Schulte
      Pages 91-98

    2. Menopause, HRT, and Hemostasis

      • P. G. Crosignani, C. Boschetti, M. Cortellaro, M. Meschia
      Pages 99-103

    3. Angina in Women

      • Peter Collins
      Pages 105-110

    4. Effect of Estrogen on Anatomical and Functional Sequelae of Coronary Artery Disease

      • G. M. C. Rosano, F. Leonardo, G. Grutter, S. L. Chierchia
      Pages 111-117

    5. Cardiovascular Disease: Reduced Mortality with Long-Term HRT Treatment

      • Göran Samsioe
      Pages 119-124

    6. HRT and the Secondary Prevention of Coronary Heart Disease

      • John C. Stevenson
      Pages 125-128
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Keywords

About this book

Despite its universality in human female aging, the menopause and its biology are not completely understood. New biologic mechanisms by which sex hormones may be detrimental or confer protection are continually being discovered.
We are now starting to understand that the role of the estrogen receptor is not identical in all tissues. Important nongenomic effects for sex hormones have also been described. Hormone replacement therapy (HRT) has produced effects on health risks: some are reduced, some are increased, and the rest remain uncertain. HRT is being used by an increasing number of women to alleviate climacteric symptoms in the perimenopausal period and to prevent osteoporosis and cardiovascular disease later. Positive effects on Alzheimer's disease and dementia on the one hand, and an increase in venous thrombosis on the other, are currently being reported by several groups. Both the preventive benefits and the risk of breast cancer seem to be linked to long-term and current use. HRT requires further testing through specific clinical trials, currently underway in the United States, before confident recommendations may be made about the full range of benefits and risks.

Editors and Affiliations

  • Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    R. Paoletti, M. R. Soma

  • Department of Obstetrics and Gynecology, University of Milan, Milan, Italy

    P. G. Crosignani

  • Department of Obstetrics and Gynaecology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands

    P. Kenemans

  • Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden

    G. Samsioe

  • Giovanni Lorenzini Medical Foundation, Houston, USA

    A. S. Jackson

Bibliographic Information

  • Book Title: Women’s Health and Menopause

  • Book Subtitle: Risk Reduction Strategies

  • Editors: R. Paoletti, P. G. Crosignani, P. Kenemans, G. Samsioe, M. R. Soma, A. S. Jackson

  • Series Title: Medical Science Symposia Series

  • DOI: https://doi.org/10.1007/978-94-011-5560-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Hardcover ISBN: 978-0-7923-4697-5Published: 31 August 1997

  • Softcover ISBN: 978-94-010-6343-2Published: 28 October 2012

  • eBook ISBN: 978-94-011-5560-1Published: 06 December 2012

  • Series ISSN: 0928-9550

  • Edition Number: 1

  • Number of Pages: XXIX, 341

  • Topics: Gynecology, Biochemistry, general, Epidemiology, Public Health

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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