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Lipoprotein Metabolism and Atherogenesis

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. Toru Kita

    1. Department of Geriatric Medicine Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto, Japan

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  2. Masayuki Yokode

    1. Department of Geriatric Medicine Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto, Japan

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    You can also search for this editor in PubMed   Google Scholar

  • Presenting the exciting results of research in the areas of the molecular basis of lipoprotein metabolism,

  • the link between lipoprotein metabolism disorder and atherogenesis, and the molecular approaches to risk factors and prevention

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Table of contents (61 papers)

  1. The Molecular Basis of Lipoprotein Metabolism (I)

    1. Inhibitory Effect of HMG-CoA Reductase Inhibitors for the Development and Progression of Intimal-medial Thickness in Carotid Artery in Type 2 Diabetes Mellitus with Hypercholesterolemia

      • Shozo Kobori, Takeshi Takahashi, Shoko Kodama, Toru Takemura, Takeshi Matsumura, Masakazu Sakai et al.
      Pages 77-79

    2. Plasma phosphatidylcholine hydroperoxide concentrations in normal subjects and patients with hyperlipidemia

      • Yasushi Ishigaki, Shinichi Oikawa, Mikio Kinoshita, Kyoko Hayasaka, Akihiro Sekikawa, Tazuko Nagashima et al.
      Pages 80-81

  2. The Molecular Basis of Lipoprotein Metabolism (II)

    1. Front Matter

      Pages 83-83
      Download chapter PDF

    2. Lipid Transfer Proteins and Receptors in HDL Metabolism

      • Alan R. Tall, Xian-cheng Jiang, Nan Wang, Takeshi Arai, David Silver
      Pages 85-87

    3. PPARs and Atherosclerosis

      • InÈs Pineda Torra, Jean-Charles Fruchart, Bart Staels
      Pages 88-95

    4. Molecular Basis of Cellular Cholesterol Efflux and Regulation of Plasma HDL Level

      • Shinji Yokoyama, Maki Tsujita, Sumiko Dohmae
      Pages 96-103

    5. Roles of Apolipoprotein E Receptors in Lipoprotein Metabolism

      • Tokuo T. Yamamoto, Yousuke Inagaki, Ryoichi X. Ioka, Shiroh Z. Yoshioka, Kenta Magoori, Man-Jong Kang et al.
      Pages 104-107

    6. The structure and function of the scavenger receptor class A

      • Takeshi Murakami, Yoshihiko Yamada, Takefumi Doi, Takao Hamakubo, Tatsuhiko Kodama
      Pages 108-114

    7. Impairment of Reverse Cholesterol Transport System and Atherosclerosis

      • Shizuya Yamashita, Takao Maruyama, Ken-ichi Hirano, Naohiko Sakai, Norimichi Nakajima, Yuji Matsuzawa
      Pages 115-123

    8. ACAT Genes and Proteins in Humans

      • T. Y. Chang, Cathy Chang, Oneil Lee, Jonathan Cruz
      Pages 124-129

    9. Caveolin is a Cholesterol-binding Protein

      • Masayuki Murata
      Pages 130-136

    10. In vivo Functions of SREBPs

      • Hitoshi Shimano, Nobuhiro Yamada
      Pages 137-141

    11. Molecular Characterization of Arachidonate Preferring Acyl-CoA Synthetase, ACS4

      • Yong-Yeon Cho, Man-Jong Kang, Hiroyuki Minekura, Shigeki Ogawa, Takahiro Fujino, Tokuo T. Yamamoto
      Pages 142-143

    12. Molecular Characterization of Short-Chain Acyl-CoA Synthetases

      • Takahiro Fujino, Hiroyuki Sato, Yuko Cho, Tokuo T. Yamamoto
      Pages 144-145

    13. Expression of the VLDL Receptor is Up-Regulated by Cell Differentiation in HL-60 Cells

      • Sadao Takahashi, Mitsuyuki Kohno, Shotaro Kosaka, Katsuhiko Masamura, Jinya Suzuki, Koji Oida et al.
      Pages 146-148

    14. Transcriptional Regulation of the Genes for Human HMG CoA Synthase and Squalene Synthase by SREBP and NF-Y

      • Jun Inoue, Ryuichiro Sato
      Pages 149-151

    15. Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages

      • Akira Miyazaki, Naomi Sakashita, Kyu Kyu Maung, Kiyoshi Takahashi, Seikoh Horiuchi, C. C. Y. Chang et al.
      Pages 152-153

    16. Relationship Between Postprandial Triglyceride Level and Intima-Media Thickness of Carotid Artery after Troglitazone Treatment in Type 2 Diabetes

      • Hiroyuki Koshiyama, Satsuki Tanaka, Jun Minamikawa, Kazuwa Nakao
      Pages 154-156

    17. A New Rabbit Strain with Heritable Hypercholesterolemia and Hypertriglyceridemia

      • Satoshi Takasaki, Chuan Zhang, Tsunekata Ito, Hitonobu Tomoike
      Pages 157-159

    18. Turnover of Glutathione and Ascorbic Acid is Suppressed in Hyperlipidemic Rabbits

      • Kuniharu Suzumura, Emiko Kasahara, Kuang-Chang Chien, Masayasu Inoue
      Pages 160-162
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Keywords

About this book

Atherosclerosis leading to coronary heart disease and to cerebrovascular disorders is the number one cause of death in industrialized societies. For the last two decades, great ad­ vances have been made in understanding the pathogenesis of those disorders. Recent studies have revealed that the earliest event in atherogenesis is the adhesion of circulating leukocytes to the vascular endothelial cells and their migration into the subendothelial space. These cells are known to playa central role in the formation of a fatty streak consist­ ing of lipid-laden foam cells. As pathological events continue, the lesion is converted to a more fibrous lesion associated with vascular smooth muscle cells. To solve the enigma of this complicated process, intensive studies in molecular biology have disclosed the genes involved in those events. Some of the genes have been verified by creation of novel animal models, which have led to novel therapeutic strategies for subjects with atherosclerosis. This volume contains papers presented at the International Symposium on Lipoprotein Metabolism and Atherogenesis held in Kyoto December 5-8, 1998, supported in part by the Japan Intractable Diseases Research Foundation. The following three topics were the focus of the three-day program: I) The molecular approach to studying risk factors and prevention 2) The creation of novel animal models 3) Lipoprotein disorder as a cause of activation of vascular endothelial cells Thirty distinguished researchers from the United States, the United Kingdom, Austria, Finland, Australia, and Japan were invited.

Editors and Affiliations

  • Department of Geriatric Medicine Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto, Japan

    Toru Kita, Masayuki Yokode

Bibliographic Information

  • Book Title: Lipoprotein Metabolism and Atherogenesis

  • Editors: Toru Kita, Masayuki Yokode

  • DOI: https://doi.org/10.1007/978-4-431-68424-4

  • Publisher: Springer Tokyo

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Tokyo 2000

  • Hardcover ISBN: 978-4-431-70261-0Published: 01 September 2000

  • Softcover ISBN: 978-4-431-68426-8Published: 25 February 2012

  • eBook ISBN: 978-4-431-68424-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 283

  • Topics: Metabolic Diseases, Programming Techniques

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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