The Genetics and Development of Scoliosis

  • Kenro Kusumi
  • Sally L. Dunwoodie

Table of contents

  1. Front Matter
    Pages i-xii
  2. Alan Rawls, Rebecca E. Fisher
    Pages 1-29
  3. Peter G. Alexander, Ricardo Londono, Thomas P. Lozito, Rocky S. Tuan
    Pages 31-61
  4. Nan Wu, Philip Giampietro, Kazuki Takeda
    Pages 89-106
  5. Zhaoyang Liu, Ryan Scott Gray
    Pages 107-138
  6. Carol A. Wise, Shiro Ikegawa
    Pages 139-157
  7. Elizabeth A. Terhune, Erin E. Baschal, Nancy Hadley Miller
    Pages 159-178
  8. Jeremy McCallum-Loudeac, Megan J. Wilson
    Pages 179-193
  9. Back Matter
    Pages 195-199

About this book

Introduction

Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. 

This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.

Keywords

anatomy morphogenesis pathology genetic counselors spine Genomic

Editors and affiliations

  • Kenro Kusumi
    • 1
  • Sally L. Dunwoodie
    • 2
  1. 1.School of Life SciencesArizona State UniversityTempeUSA
  2. 2.Developmental and Stem Cell Biology DivisionVictor Chang Cardiac Research InstituteSydneyAustralia

Bibliographic information

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